Sathish Kumar Munusamy Email & Phone Number

Technical and market research for Bioplastic industries. Conducted secondary market research for Bioplastics and Algae Nutraceutical Industries.

Brigham And Women'S Hospital, Boston, Ma

Personalized genetic testing of cancer using next-generation sequencing with Rapid Heme Panel.

Co-ordination for Clinical Trials Served as a point-of-contact for multiple studies and collaborations. Managed end-to-end sample processing in clinical trials.  Documented study results, research data, process and workflow. Held meetings with principal investigators to provide recommendations and updates.  Tracked study progress and communicated project trackers with stakeholders regularly. Managed supplies and inventory by coordinating with vendors… Show more Co-ordination for Clinical Trials Served as a point-of-contact for multiple studies and collaborations. Managed end-to-end sample processing in clinical trials.  Documented study results, research data, process and workflow. Held meetings with principal investigators to provide recommendations and updates.  Tracked study progress and communicated project trackers with stakeholders regularly. Managed supplies and inventory by coordinating with vendors.  Established new workflow for prevention of delays and projects. Clinical Research and Diagnosis  Performed next-generation sequencing and gene expression analysis on tissue samples using nCounter Analysis System from NanoString Technologies.  Validated laboratory for new diagnostic procedure – PAM50 - PROSIGNA breast cancer assay.  Developed Standard Operating Procedures (SOP) for routine testing of specimens through nCounter assays. Trained newly employed technologists in diagnostic techniques and methods. Show less

Albany Area, New York

Modulation of Hsp27 chaperone activity using RNA aptamers.• Developed RNA aptamers for oligomeric form of Hsp27 protein using in-vitro selection/evolution.• Performed minimization and characterization of RNA aptamer molecules. • Synthesized RNA libraries using in-vitro transcription and enzymatic manipulations. • Created deletion constructs and site-directed mutagenesis in wild-types genes.• Purified recombinant proteins by chromatographic techniques – HPLC, FPLC, SEC… Show more Modulation of Hsp27 chaperone activity using RNA aptamers.• Developed RNA aptamers for oligomeric form of Hsp27 protein using in-vitro selection/evolution.• Performed minimization and characterization of RNA aptamer molecules. • Synthesized RNA libraries using in-vitro transcription and enzymatic manipulations. • Created deletion constructs and site-directed mutagenesis in wild-types genes.• Purified recombinant proteins by chromatographic techniques – HPLC, FPLC, SEC, Ion-Exchange (IEX). • Prepared protein targets for In-Vitro Selection (SELEX) using dialysis, membrane-filtration and buffer-exchange. • Characterized proteins using UV Absorption Spectrometry, CD Spectroscopy, Dynamic Light Scattering, Western Blot, ELISA and gel electrophoresis. • Developed cell-based protein activity assays and performed RNA-protein binding assays (EMSA) and in-vitro chaperone activity assays. Show less

Albany, New York Area

Generating RNA aptamers for molecular chaperone, Hsp90. • Developed RNA aptamers for Hsp90β through in-vitro selection using nitrocellulose. • Analyzed pitfalls and problems that occur during in-vitro selection process.

Albany, New York Area

Functional analysis of S-protein mutations in lambda phage. • Transformation of phage DNA containing single nucleotide mutations at each position of S- protein coding gene. • Phage propagation and quantification by plaque formation assay.

Chennai Area, India

Data mining and simulation of endothelial nitric oxide synthase pathway in cardiac smooth muscle cells.

Chennai Area, India

Isolated and characterized freshwater magnetotactic bacteria using specialized microbiological techniques.I conceived the project with the aim of isolating magnetosomes from inside bacteria and studying their properties.

Master'S Degree, Molecular Biology

Modulation of Hsp27 chaperone activity using RNA aptamers. • Design & execution of novel aptamer generation strategy for oligomeric.

Bachelor Of Technology (B.Tech.), Industrial Biotechnology

Multi-disciplinary foundations in Industrial Biotechnology, Bioprocess, Biological, Engineering and Management principles. Performed.