Sofia Francisco B. Email & Phone Number

Maryland, United States

Curtis Bay, Maryland

Baltimore, Maryland, United States

Curtis Bay, Maryland

Curtis Bay, Maryland

Developed robust and scalable downscale study of ultra-filtration membranes and large scale implementation in a cGMP environmentAuthored and revised batch records, in-process specifications, protocols, raw material components, and standard operating procedure and associated justification documentationMaintained personal training record to ensure cGMP complianceCollaborated with QA to successfully implement corrective actions based on deviationsReviewed executed manufacturing documentation for completeness, while trending data for continued process improvementPerformed Agilent Lab-on-a-Chip electrophoresis and chromatographic separation (NR-CE-SDS), SE-HPLC for monomer quantification, and small scale protein purification using AKTADeveloped DOE for small scale purification studies regarding, Pro-A, Hydroxyapatite resin, Q-membrane, nanofiltration, and UF/DF for large scale implementation at the clinical levelTrended data via statistical analysis from DOE and real time data collectionPerformed successful technical transfer from lab scale to pilot scale productionExecuted and implemented cleaning validation for reusable components

Method development utilizing the AKTA pilot for liquid based chromatographyManufacturing of cGMP clinical lots for multiple antibodies in a single use environment Operation and maintenance of the Shimadzu Total Organix Carbon (TOC) Resin selection for different molecules and binding domains including Fc expression and albuminPacking and column evaluation/integration of MAb Select and Hydroxyapatite resinChemistry Undergraduate Preparation Laboratory April 2009 – May 2011 University of Maryland, Baltimore County Supported 46 undergraduate teaching laboratories via preparation of chemical reagents, experimental setups and instrumentation Developed an effective and efficient method that reduced laboratory preparation time by 25%Revamped ordering procedure to increase productivity by 50 % while ensuring chemical and glassware inventories were maintained for continuous serviceKnowledge of OSHA/MIOSHA chemical storage and disposal regulations

Umbc

Supported 46 undergraduate teaching laboratories via preparation of chemical reagents, experimental setups and instrumentation Developed an effective and efficient method that reduced laboratory preparation time by 25%Revamped ordering procedure to increase productivity by 50 % while ensuring chemical and glassware inventories were maintained for continuous serviceKnowledge of OSHA/MIOSHA chemical storage and disposal regulations

Responsible for teaching a class of 48 students per weekConducted weekly tutoring sessions with students Attended weekly meetings with the teaching faculty

Master Of Business Administration - Mba

Bachelor Of Science, Chemical Engineering (Chemistry)