Som Dev Email and Phone Number
Som Dev personal email
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I am a motivated research professional with several years of experience in Molecular Cell Biology, and Biochemistry Research and worked on the role of micronutrients especially redox active metals (Iron and Copper) in anemia, thalassemia, hemochromatosis and Wilson disease respectively. Presently, I am working as an assistant professor in the Dept. of Biochemistry, AIIMS Kalyani, India. I had extensive training in research and laboratory technology, starting with BSc MLT in IGMC Shimla followed by Masters in Biochemistry at Postgraduate Institute of Medical Education and Research Chandigarh where I worked on folic acid uptake and transport mechanism during folate over-supplementation model to understand birth defects (Dev et al, BJN 2011). I continued my work on understanding the role of iron and Cu in my doctoral (Dev et al, FRBM 2016) and postdoctoral (Dev et al, Science Advances 2022, Hepatology 2020, co-authored several publications in Hepatology 2019, American Journal of Hematology 2019, American Journal of Pathology 2022, PNAS 2023 & Blood 2023) training. I got training from JNU for 6 year and postdoctoral training from Harvard-MGH and Johns Hopkins Medicine for 7 years to understand pathogenesis of anemia, b-thalassemia hemochromatosis, and Wilson disease. I have vast expertise in biochemistry, cellular and molecular biology techniques, transgenic mice generation and working on murine (disease) models. I have 16 indexed publications, 1 Book chapter, an h-index 12 with more than 1000 citations.In AIIMS, I focussed my research on understanding role of metals in medicine especially hemoglobinopathies, neurodegenerative disorders and WD and imparting clinically oriented and interactive teaching for biomedical and paramedical students apart from routine clinical biochemistry & molecular services and validation.
Aiims Kalyani
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Assistant ProfessorAiims Kalyani Jul 2023 - PresentWest Bengal, India
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Postdoctoral ResearcherThe Johns Hopkins University School Of Medicine Feb 2019 - Jul 2023Baltimore, Maryland AreaKabin E, Dong Y, Roy S, Smirnova J, Smith JW, Ralle M, Summers K, Yang H, Dev S, Wang Y, Devenney B, Cole RN, Palumaa P, Lutsenko S. α-lipoic acid ameliorates consequences of copper overload by up-regulating selenoproteins and decreasing redox misbalance. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2305961120. doi: 10.1073/pnas.2305961120. Epub 2023 Sep 26. PMID: 37751556Dev S, Muchenditsi A, Gottlieb A, Deme P, Murphy S, Gabrielson KL, Dong Y, Hughes R, Haughey NJ, Hamilton JP… Show more Kabin E, Dong Y, Roy S, Smirnova J, Smith JW, Ralle M, Summers K, Yang H, Dev S, Wang Y, Devenney B, Cole RN, Palumaa P, Lutsenko S. α-lipoic acid ameliorates consequences of copper overload by up-regulating selenoproteins and decreasing redox misbalance. Proc Natl Acad Sci U S A. 2023 Oct 3;120(40):e2305961120. doi: 10.1073/pnas.2305961120. Epub 2023 Sep 26. PMID: 37751556Dev S, Muchenditsi A, Gottlieb A, Deme P, Murphy S, Gabrielson KL, Dong Y, Hughes R, Haughey NJ, Hamilton JP, Lutsenko S. Oxysterol misbalance critically contributes to Wilson disease pathogenesis. Sci Adv. 2022 Oct 21;8(42):eadc9022. doi: 10.1126/sciadv.adc9022. Epub 2022 Oct 19. PMID: 36260680 https://www.science.org/doi/10.1126/sciadv.adc9022Dev S, Kruse RL, Hamilton JP, Lutsenko S. Wilson Disease: Update on Pathophysiology and Treatment. Front Cell Dev Biol. 2022 May 2;10:871877. doi: 10.3389/fcell.2022.871877. PMID: 35586338Dev S, Hamilton JP. Wilson Disease: Epigenetic Factors Contribute to Genetic Mutations to Affect the Disease. Cell Mol Gastroenterol Hepatol. 2021;12(4):1507-1508. PMID: 34352219.Gottlieb A, Dev S, DeVine L, Gabrielson KL, Cole R, Hamilton JP, and Lutsenko S. Hepatic steatosis development in the mouse model of Wilson disease coincides with a muted inflammatory response. The American Journal of Pathology, 2021; S0002-9440 (21)00435-1. PMID: 34627751.Muchenditsi A, Talbot Jr CC., Gottlieb A, Yang H, Kang B, Boronina T, Cole R, Wang L, Dev S, Hamilton JP, and Lutsenko S. Systemic deletion of Atp7b modifies the hepatocytes’ response to copper overload in the mouse models of Wilson disease. Scientific Reports. 2021;11:5659. PMID:33707579.Yang H, Liu CN, Wolf RM, Ralle M, Dev S, Pierson H, Askin F, Steele KE, Magnuson TH, Schweitzer MA, Wong GW, Lutsenko S. Obesity is associated with copper elevation in serum and tissues. Metallomics. 2019;11:1363-1371. PMID: 31249997. Show less -
Postdoctoral FellowHarvard Medical School - Massachusetts General Hospital Sep 2016 - Feb 2019Boston, MassachusettsXiao X, Moschetta GA, Xu Y, Fisher AL, Alfaro-Magallanes VM, Dev S, Wang CY, Babitt JL. Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in β-thalassemia. Blood. 2023 Jan 26;141(4):422-432. doi: 10.1182/blood.2022017811. PMID: 36322932 https://doi.org/10.1182/blood.2022017811Xiao X#, Dev S#, Canali S, Bayer A, Xu Y, Agarwal A, Wang CY, Babitt JL. Endothelial Bone Morphogenetic Protein 2 (Bmp2) Knockout Exacerbates Hemochromatosis in… Show more Xiao X, Moschetta GA, Xu Y, Fisher AL, Alfaro-Magallanes VM, Dev S, Wang CY, Babitt JL. Regulation of iron homeostasis by hepatocyte TfR1 requires HFE and contributes to hepcidin suppression in β-thalassemia. Blood. 2023 Jan 26;141(4):422-432. doi: 10.1182/blood.2022017811. PMID: 36322932 https://doi.org/10.1182/blood.2022017811Xiao X#, Dev S#, Canali S, Bayer A, Xu Y, Agarwal A, Wang CY, Babitt JL. Endothelial Bone Morphogenetic Protein 2 (Bmp2) Knockout Exacerbates Hemochromatosis in Homeostatic Iron Regulator (Hfe) Knockout Mice but not Bmp6 Knockout Mice. Hepatology. 2020;72:642-655. PMID: 31778583. #Co-first author.Wang CY, Xiao X, Bayer A, Xu Y, Dev S, Canali S, Nair AV, Masia R, Babitt JL. Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice. Hepatology. 2019;70:1986-2002. PMID: 31127639.Wang CY, Canali S, Bayer A, Dev S, Agarwal A, Babitt JL. Iron, erythropoietin, and inflammation regulate hepcidin in Bmp2-deficient mice, but serum iron fails to induce hepcidin in Bmp6-deficient mice. American Journal of Hematology. 2019;94:240-248. PMID: 3047885.Dev S, Babitt JL. Overview of iron metabolism in health and disease. Hemodial Int. 2017; Suppl 1:S6-S20. PMID: 28296010. Show less -
Graduate StudentSpecial Centre For Molecular Medicine, Jawahar Lal Nehru University Aug 2010 - May 2016New Delhi, IndiaMukherjee A, Dev S, Ghosh E, Asthana S, Mukhopadhyay CK. Astroglial iron homeostasis and neurodegenerative diseases. I. Patro (Eds.): The Biology of Glial Cells: Recent Advances 2022 (Springer Nature, Singapore).Dev S, Kumari S, Singh N, Kumar Bal S, Seth P, Mukhopadhyay CK. Role of extracellular hydrogen peroxide in regulation of iron homeostasis genes in neuronal cells: Implication in iron accumulation. Free Radic Biol Med. 2015;86:78-89. PMID: 26006106.Singh N, Haldar S… Show more Mukherjee A, Dev S, Ghosh E, Asthana S, Mukhopadhyay CK. Astroglial iron homeostasis and neurodegenerative diseases. I. Patro (Eds.): The Biology of Glial Cells: Recent Advances 2022 (Springer Nature, Singapore).Dev S, Kumari S, Singh N, Kumar Bal S, Seth P, Mukhopadhyay CK. Role of extracellular hydrogen peroxide in regulation of iron homeostasis genes in neuronal cells: Implication in iron accumulation. Free Radic Biol Med. 2015;86:78-89. PMID: 26006106.Singh N, Haldar S, Tripathi AK, Horback K, Wong J, Sharma D, Beserra A, Suda S, Anbalagan C, Dev S, Mukhopadhyay CK, Singh A. Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities. Antioxid. Redox Signal. 2014; 20:1324–63. PMID: 23815406. Mukhopadhyay CK, Dev S, Tapryal N, Mukherjee R, Mukhopadhyay C. Role of redox and ceruloplasmin in iron deposition in glial cells: Implication in neurodegenerative damages. IIOAB J. 2011; 2:1–9. Show less
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Masters StudentPost Graduate Institute Of Medical Education And Research, Chandigarh Aug 2008 - Jul 2010Chandigarh, IndiaDev S, Ahmad Wani N, Kaur J. Regulatory mechanisms of intestinal folate uptake in a rat model of folate oversupplementation. Br J Nutr. 2011;105:827-35. PMID: 21092376.Thakur S, Thakur SD, Wani NA, Kaur J. Reduced expression of folate transporters in kidney of a rat model of folate oversupplementation. Genes Nutr. 2014;9:369. (PMID: 24306960).
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Senior Laboratory TechnicianDr. Rajendra Prasad Government Medical College 2007 - 2008Kangra, H.P.Job was to perform blood grouping (ABO and Rh) on patients/ patient samples. Screening/testing of blood for blood-borne pathogens ( HIV, Hepatitis B, C, Plasmodium etc) before issuing for transfusion.Organize and assist in blood collection from donation camp.Round the clock duty for 1 year.
Som Dev Skills
Som Dev Education Details
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Molecular Medicine -
Post Graduate Institute Of Medical Education And Research (Pgimer), ChandigarhMedical Biochemistry -
Medical Lab Technology
Frequently Asked Questions about Som Dev
What company does Som Dev work for?
Som Dev works for Aiims Kalyani
What is Som Dev's role at the current company?
Som Dev's current role is Assistant Professor-Biochemistry, All India Institute of Medical Sciences, Kalyani.
What is Som Dev's email address?
Som Dev's email address is so****@****ail.com
What schools did Som Dev attend?
Som Dev attended Jawaharlal Nehru University, New Delhi, Post Graduate Institute Of Medical Education And Research (Pgimer), Chandigarh, Indira Gandhi Medical College, Shimla.
What skills is Som Dev known for?
Som Dev has skills like Research.
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