Sonal Kothari-Gupta, Md, Phd Email and Phone Number
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Sonal Kothari-Gupta, Md, Phd personal email
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Physician/Scientist with 18 plus years of experience in Cell and gene therapy/Gene editing, Immuno-oncology, CAR-T cell therapy, Solid Tumors, Lysosomal storage diseases, Rare Diseases, Lentiviral gene therapy, CRISPR gene editing, ex vivo CD34+ stem cell transplant, Artificial antigen presenting cells, Immunology, Hemoglobinopathies, IND/CTA, clinical development, clinical trial design and execution, Clin-Regulatory strategy, clinical biomarkers, clinical exploratory research, clinical pharmacology, systems biology, statistical programming, biostatistics, companion Dx, IUO tests, vendor management, seasoned leader, team builder, alliance management.Specialties: Immuno-Oncology clinical development, clinical trial design and execution, translational medicine, innovative trial design, medical monitoring, clinical data management, clinical data interpretation, investor presentations, clinical biomarker strategy, bioanalysis, pre-clinical to clinical translation and modeling, assay Development, regulated research-GLP, GMP, CAP/CLIA, inflammation and immunology, and immuno-oncology, rare disease and ultra rare disease
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Chief Medical OfficerCoregen Inc.Lexington, Ma, Us
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Senior Vice President, Head Of Clinical DevelopmentAffyimmune Therapeutics Apr 2022 - PresentNatick, Massachusetts, UsTherapeutic area expertise: Rare cancers, NSCLCIn my role as Senior Vice President at AffyImmune Therapeutics, I am spearheading the clinical development and regulatory strategies for autologous CAR T cell trials in aggressive solid tumors. By leading cross-functional teams and driving the R&D strategy, have successfully advanced Phase 1/2/Pivotal trials in thyroid and lung cancers, contributing to the advancement of innovative treatments in oncology. Part of the senior executive team, working closely with the CEO, CMC/manufacturing, Quality Assurance, Finance and Operations, and Program Leadership functions. Cultivated relationships with principal investigators, patient advocacy groups, key opinion leaders (KOLs) and members of the broader medical and scientific communities. Build and lead high functioning Clinical Development organization. Experience in regulatory interactions (e.g., RMAT and other regulatory milestones) -
Head Of Translational Medicine At AvrobioAvrobio Jun 2020 - Apr 2022Cambridge, Massachusetts, UsHeading Translational Medicine for Lysosomal storage diseases, Rare Diseases/Ultra rare diseases, Lentiviral gene therapy, ex vivo CD34+ stem cell transplant, Immunology, IND/CTA, Clinical trial design and execution, Clinical development, Clinical biomarkers, Clinical exploratory research, Clinical pharmacology, Systems biology, Statistical programming, Biostatistics, Vendor management, Seasoned leader, Team builder and Alliance management. Experience in Innovative trial design, medical monitoring, clinical data management, clinical data interpretation, investor presentations, clinical biomarker strategy, bioanalysis, pre-clinical to clinical translation and modeling, assay development, and regulated research-GLP, GMP, CAP/CLIA -
Senior Director, Head Of Translational ResearchRubius Therapeutics Sep 2019 - Jun 2020Cambridge, Massachusetts, Us -
Director, Head Of Preclinical And Clinical AssaysCrispr Therapeutics Jul 2016 - Aug 2019Boston, Ma, UsBuilt and was leading a world class bioanalytical and translational/exploratory biomarker assay group that is managing the development and implementation of IND-enabling, GLP and GCLP quality assays in support of preclinical and tox studies and clinical trial endpoints and translational/exploratory biomarkers. Strategic leadership and experienced mentorship to PhD scientists and RAs and global vendor management. Bioanalytical leader in cross-functional project teams. Deep experience in various disease areas, such as hemoglobinopathies, and the field of Immuno-oncology (CAR-T cells based therapies) for hematological malignancies, and Gene Editing/Cell based hybrid drug product therapies. -
Manager, Bioanalytical GroupSelecta Biosciences Apr 2015 - Jul 2016
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Senior Research ScientistCambridge Biomedical Inc. Sep 2011 - Apr 2015Flow Cytometry, Luminex, GLP and non-GLP quality level assay development and validation.
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Bioanalytical Assay Development ScientistShire Human Genetic Therapies Inc Jan 2009 - Dec 2010 -
Postdoctoral Research FellowDepartment Of Gastroenterology, Mass General Hospital, Boston, Ma Apr 2006 - Dec 2008I was working as a postdoctoral research fellow in the gastrointestinal unit (GI unit) in the Department of medicine at the Massachusetts General Hospital in Boston. My work involves analyzing the immunological response of the body to colorectal cancer in wildtype and gene knockout mouse models.
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Phd StudentUniversity Of Bradford Sep 2001 - Oct 2004Bradford, West Yorkshire, GbPhD student in Biomedical SciencesThe research group I worked with during my PhD has a major interest on vitiligo, and malignant melanoma. I have worked extensively with transcription factors, especially HNF-1 α(hepatocyte nuclear factor-1 α and p53. Multiple immunological markers were used to differentiate clinically similar leukodermas, such as that associated with vitiligo and leukodermas associated with malignant melanoma, dysplastic naevus and halo naevus.I successfully defended my PhD thesis in October 2005. The title of the thesis is ‘A comparative study of clinically similar leukodermas using DCoH/HNF1 αexpression as a marker for transcriptional analyses.'' -
Medical DoctorGovernment Medical College Jan 1993 - Jan 1999
Sonal Kothari-Gupta, Md, Phd Skills
Sonal Kothari-Gupta, Md, Phd Education Details
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University Of BradfordOncology And Cancer Biology -
South Gujarat UniversityMedicine
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High School
Frequently Asked Questions about Sonal Kothari-Gupta, Md, Phd
What company does Sonal Kothari-Gupta, Md, Phd work for?
Sonal Kothari-Gupta, Md, Phd works for Coregen Inc.
What is Sonal Kothari-Gupta, Md, Phd's role at the current company?
Sonal Kothari-Gupta, Md, Phd's current role is Chief Medical Officer.
What is Sonal Kothari-Gupta, Md, Phd's email address?
Sonal Kothari-Gupta, Md, Phd's email address is so****@****bio.com
What schools did Sonal Kothari-Gupta, Md, Phd attend?
Sonal Kothari-Gupta, Md, Phd attended University Of Bradford, South Gujarat University, High School.
What are some of Sonal Kothari-Gupta, Md, Phd's interests?
Sonal Kothari-Gupta, Md, Phd has interest in Children, Civil Rights And Social Action, Politics, Environment, Education, Poverty Alleviation, Science And Technology, Disaster And Humanitarian Relief, Human Rights, Animal Welfare.
What skills is Sonal Kothari-Gupta, Md, Phd known for?
Sonal Kothari-Gupta, Md, Phd has skills like Cell Culture, Assay Development, Elisa, Cell, Flow Cytometry, Immunology, Cell Biology, Oncology, Gmp, Western Blotting, Dna, Immunohistochemistry.
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