Sonya Clark Email and Phone Number
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As a well-respected Molecular Cell Biologist, I offer a strong technical background in managing data science programs and projects spanning synthetic biology integrating genomics, molecular and cell biology, protein engineering, bioinformatics, automation, and business systems. By tackling deep technical challenges via team collaboration and leadership, I excel as a proficient expert, influencing discovery of innovative solutions for leading market edge products. Areas of strength include:► PROJECT MANAGEMENT LEADER, within startup and established companies, delivering statistical data-driven results to solve complex challenges.► PROTEIN ENGINEERING EXPERT, in creating molecules for sequencing applications, and driving process development for automated data systems integration.► CREATIVE PROBLEM-SOLVER, skilled in experimental design (DOE) and data analysis. Hands-on data-miner and analyzer of complex genomic data.► INNOVATIVE PRODUCT & MARKET DISRUPTOR, with achieved technology development for RUO and regulated synthetic biology products.Contributing a unique blend of business and analytical acumen, I bring to the table an accomplished record of experiences and skill assets. Selected areas of career impact include: ✓Built strong program for creating variant libraries for protein and antibody engineering that grew ~10x in revenue.✓Improved productivity and alignment with integration of fully functional program strategies.✓Spearheaded protein engineering team that managed invention, discovery, and optimization of enzyme entities.✓Championed significant amounts of IP, infrastructure expansion, and execution of selection / characterization activities.✓Cultivated teams of experts. Led laboratory restructuring via automation to support growing product pipelines.✓Influenced industry decision-makers via history of various publications and technical documentation.KEY SKILLS: Product Design & Development | Complex Data Research & Analysis | Testing & Validation | Process Control | Data Modeling & Visualization | Bioinformatics | Molecular Cloning & Genetics | Failure Mode & Effects Analysis | Intellectual Property | Biochemistry | DNA Sequencing & Extraction | Structural Biology | Tissue & Cell Cultures | Gene Expression | Biotechnology | Fermentation | Biomarker | Machine Learning | Lean Manufacturing | ISO 9000
10X Genomics
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Director Of Protein Engineering10X Genomics Jul 2019 - PresentPleasanton, California, UsSteered creation and implementation of sophisticated, protein evolutionary strategies. Oversaw team operations and developed workflow roadmaps, labs, and lab processes. Defined highly technical engineering direction as well as NGS data pipelines. Collaborated cross-functionally to mine sequence data to explore enzymatic behaviors. Designed and drove validation of wet lab screening methods. Cultivated CRO relationships and spearheaded team to support transfer of new enzymes.● Propelled five enzymes into product pipelines that more than doubled overall sensitivity and performance of new on-market products. Navigated enzyme transfer into multiple products during development and into product release.● Excelled in leading bottom-up build of protein engineering function targeting 10xG needs. Designed full program by gathering requirements for deliverables and coordinating activity of facilities team to build physical space.● Demonstrated sound judgement in hiring and managing seven-member staff. Crystalized strategy and technical direction while guiding focused approach and coordinating collaboration amongst scientific programs.● Tripled lifespan of enzyme reaction by implementing more fail-safe solution for higher stability of new product line. Achieved five-fold decrease in labor efforts by convening team of experts to explore and pinpoint solutions.
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Director Technology Transfer And Variant Library Project ManagerTwist Bioscience Aug 2016 - May 2019South San Francisco, California, UsExcelled with increased responsibility to lead end-to-end product development focusing on DNA variant libraries for protein and antibody engineering. Created growth-oriented budget and staffing plans. Drove validated release of highly complex bioinformatic pipelines. Interfaced with customers and engaged cross-functional business units.● Championed release of multiple products into production under RUO and ISO CFR 13485 requirements. Designed, analyzed, and generated reports for all development experiments to meet regulatory requirements.● Designed and drove infrastructure implementations, from order intake and automated lab systems to required documentation and customer-facing QC release processes. Designed and performed hands-on process testing.● Built out functional department producing complex molecular biology product that leveraged Twist core capability in producing high complexity DNA molecules. Hired team and defined goals in specific product market.● Achieved extended viability of product line. Expanded lab capabilities and drove market growth by guiding technology improvements to ensure sustainable infrastructure.● Boosted customer base two-fold by leading team success in generating deliverable products two-times faster.● Recruited and led secondary team of experts with different deliverable for new product line innovation. Partnered with QA to ensure processes and quality requirements met regulatory needs.● Tripled throughput while cutting turn-around time 50%. Supported genomic product portfolio growth.● Propelled ~10x growth of variant libraries program. Oversaw development programs for (amplified) oligo pools (for NGS target enrichment / capture applications). -
Principal Scientist, Biochemistry R&D - Tech Development Group LeadComplete Genomics Inc. /Bgi Sep 2010 - Dec 2015Fostered stabilized production environment. Organized and managed design & analysis (DOE) studies across organizations to qualify and validate complex systems and modifications, including clinical validation for new sequencing technology. Specialized in development and optimization of enzymatic amplification technologies for NGS (e.g., PCR, MDA).● Rebuilt early-stage technology into comprehensive product resulting in manufacturing team boosting turn-around time of genome data set generation by third of initial situation and 10x improved quality.● Cultivated and deployed front-line team in creating lean manufacturing environment for rapid delivery. Generated highly robust customer-centric process via strong experimental approaches and deep data analysis.● Scaled prod-lab from pilot to >3000 samples p/mth. Focused on high throughput system based on integrated robotics.● Maintained production of high-quality whole genome sequencing data through sharp troubleshooting of process and biochemistry issues from enzyme quality to workflow redesigns and automation scale-up.● Orchestrated transfer of novel technologies from research to production, including Long Fragment Read systems, whole exome, and other capture products for new technologies (Revolocity High Throughput Sequencing System).
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Staff Scientist & Group Leader, Protein EngineeringPacific Biosciences Oct 2005 - Jul 2010Menlo Park, Ca, Us● Defined and directed laser-focused approach for enzyme engineering requirements while ensuring technical core technology equipped capability of delivering to intended market.● Strengthened company infrastructure by crafting in-house strategy, implementing specialized department in all aspects of enzyme engineering, from molecular biology and high-throughput screening operation through characterization and testing at application level.● Piloted team of subject matter experts in delivering 300+ highly specialized molecules that boosted technical quality and accuracy of R&D team 20-fold. Advanced team growth via supportive mentoring and guidance. ● Designed 15+ assays on various instruments to determine enzyme kinetic parameters. Built and implemented enzyme assays designed to quantitatively measure kinetic attributes of polymerases at single-molecule level. -
Staff Scientist - R&D Lead, Molecular BiologyApplied Biosystems Inc May 2002 - Jul 2005Waltham, Ma, Us● Steered development of microarray device and reagent kits. Pinpointed key issues and critical parameters in product quality and process with elevation in product quality, consistency, and finished goods yield (>15%).● Lowered product line cost by 30% while maintaining quality of successfully released-to-market product.● Optimized and validated polymerase performance for RNA/DNA labeling kits.● Leveraged early career experience gained as Sr. Scientist at BioMarin Pharmaceutical in Novato, CA.
Sonya Clark Skills
Sonya Clark Education Details
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University Of CanterburyGenetics
Frequently Asked Questions about Sonya Clark
What company does Sonya Clark work for?
Sonya Clark works for 10x Genomics
What is Sonya Clark's role at the current company?
Sonya Clark's current role is Accomplished Scientific leader specializing in: Synthetic Biology, Genomic Reagent Product Innovation and Protein Engineering 9x Patent Holder, 9x Product Innovator.
What is Sonya Clark's email address?
Sonya Clark's email address is so****@****ail.com
What is Sonya Clark's direct phone number?
Sonya Clark's direct phone number is +140488*****
What schools did Sonya Clark attend?
Sonya Clark attended University Of Canterbury.
What are some of Sonya Clark's interests?
Sonya Clark has interest in Computers, Aviation, Exercise, Home Improvement, Presentation And Formatting, Reading, Gourmet Cooking, Sports, Microsoft Visio, Fishing.
What skills is Sonya Clark known for?
Sonya Clark has skills like Word Processing, Microsoft Word, Powerpoint, Microsoft Excel, Diagrams, Forms, Transcription Services, Typing, Pdf, Ocr, Audio Typing, Copy Typing.
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