My PhD research focused on improving Out-Of-Distribution (OOD) generalization in AI—developing models that adapt to novel situations. Machine Learning models are limited by their training data, which often fails to capture real-world complexities. These OOD samples, differing from training data, remain a significant challenge for modern AI systems. Looking for jobs at the intersection of AI and Finance starting Oct 2024-Jan 2025.
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Cto And Co-FounderMemory MachinesSan Francisco, Ca, Us -
Research Assistant (Phd)Harvard University Aug 2019 - PresentCambridge, Massachusetts, United StatesMy research focusses on Out-Of-Distribution generalization---enabling AI to perform well in situations not encountered in the training data. In my PhD I have worked on:- AI Algorithms: Developed algorithms to improve generalization capabilities of AI models under distribution shifts in 3D viewpoints, scene lighting, and object materials, among others.- Machine Learning Theory: Developed theoretical underpinnings of OOD generalization to identify attributes of robust machine learning representations.- Comparing Humans and AI agents: Humans serve as an upper bound for AI. We benchmarked how well modern vision models and LLMs compare to humans under distribution shifts. [8, 9]- Generalization in Macaque Brains: Investigated generalization in-vivo through Electro-physiological recordings from Macaque Brains to understand when and how brains generalize under distribution shifts.Full list of publications: https://scholar.google.com/citations?user=QY5OAIMAAAAJ -
Teaching FellowHarvard University Jan 2022 - May 2022Cambridge, Massachusetts, United StatesTeaching fellow for Professor Gabriel Kreiman's class on Biological and Artificial Intelligence (Neuro 240):- Awarded a Teaching Distinction Award by the Derek Bok Center for Teaching for my role.- The class was a semester-long project based class, and I was single handedly in-charge of helping over 40 students with their projects. I was awarded a Teaching Award by the Derek Bok Center for -
Research InternAdobe May 2019 - Aug 2019Seattle, Washington, United StatesInvestigating if generative AI models can create out-of-distribution lighting: - Implemented a procedural graphics pipeline to create photorealistic cities under changing lighting.- Investigated lighting variations generated by Generative AI models (GANs) trained on the above dataset to evaluate utility of GenAI for Adobe’s photo-relighting efforts. -
Research Associate (Master'S)Harvard University Aug 2016 - Aug 2019Cambridge, Massachusetts, United StatesWorked in collaboration with MIT on building large-scale, controlled datasets to evaluate AI models.- Computer Graphics: Implemented a procedural graphics pipeline to create photorealistic cities with fine-grained control over scene parameters including object viewpoints, light source distribution and intensity, and scene layout, resulting a novel dataset to study behaviour Computer Vision models.- Generalization in AI: Investigated generalization behaviour of visual recognition models using above mentioned dataset, leading to a publication -
Research AssociateMicrosoft May 2018 - Apr 2019Redmond, Washington, United StatesWorked on building ChatBots with a Persona.- Developed an algorithm for non-parametric reservoir sampling—given a seed data distribution, our algorithm searches and picks samples from the internet to increase data size with minimal changes to the data distribution.- Created custom conversational agents for Microsoft Xbox. These agents used the above algorithm to build their own training datasets by sampling relevant lines similar to a given seed. -
Research AssociateUniversity Of Pennsylvania Jul 2015 - Dec 2015Philadelphia, Pennsylvania, United StatesWorked on Machine Learning models for targeted genome editign:- Conceptualized and implemented an algorithm for designing targeted molecular scissors (zinc proteins) for cleaving DNA at desired target locations.- Using a mixture of synthetic and experimental data generated using molecular docking simulations, trained an ensemble of neural networks to predict DNA-Protein interactions.This work led to two publications (available here: https://scholar.google.com/citations?user=QY5OAIMAAAAJ)
Spandan Madan Education Details
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Computer Science -
Computational Science -
Bachelor Of Technology - Btech
Frequently Asked Questions about Spandan Madan
What company does Spandan Madan work for?
Spandan Madan works for Memory Machines
What is Spandan Madan's role at the current company?
Spandan Madan's current role is CTO and Co-Founder.
What schools did Spandan Madan attend?
Spandan Madan attended Harvard University, Harvard University, Indian Institute Of Technology, Delhi.
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