Key responsibilities include (but not limited to):* Responsible for development of analytical methods for small molecules and peptide drug products.* Actively involved in product development strategy (ANDA and 505(b)(2)NDA) to ensure successful project delivery within the laid down parameters of time and cost.* Mitigate risks proactively by monitoring project progress against identified risks, tracking deliverables, reviewing milestones, and providing feed back to the team to ensure… Show more Key responsibilities include (but not limited to):* Responsible for development of analytical methods for small molecules and peptide drug products.* Actively involved in product development strategy (ANDA and 505(b)(2)NDA) to ensure successful project delivery within the laid down parameters of time and cost.* Mitigate risks proactively by monitoring project progress against identified risks, tracking deliverables, reviewing milestones, and providing feed back to the team to ensure timely execution.* Drive effective project communication to ensure sound decision by participating in cross functional project team meetings and sharing consistent information across stakeholders.* Ensure continuous improvement of internal processes and project execution by monitoring progress for smooth functioning of the projects.* Analysis of raw materials, intermediates, and finished drug products. * Participates in the out of specification investigations, as well as other investigations, and write up of the investigation reports.* Method validation during development of an analytical method.* Quantification of low-level impurities in the final APIs and finished drug products.* Maintenance and calibration of analytical equipment in compliance with cGMP.* Review of analytical laboratory records. Show less

The goal of the project: Identifying protein partners of DNA topoisomerase I, a novel drug target in Mycobacterium tuberculosis. The outcome of this research would have a far-reaching role in the development of novel drugs against tuberculosis pathogen. ♣ Designed and worked on multiple projects related to the protein-protein interactions of an essential drug target, DNA topoisomerase I.♣ Molecular docking studies, Site-directed mutagenesis.♣ Created E. coli clones… Show more The goal of the project: Identifying protein partners of DNA topoisomerase I, a novel drug target in Mycobacterium tuberculosis. The outcome of this research would have a far-reaching role in the development of novel drugs against tuberculosis pathogen. ♣ Designed and worked on multiple projects related to the protein-protein interactions of an essential drug target, DNA topoisomerase I.♣ Molecular docking studies, Site-directed mutagenesis.♣ Created E. coli clones over-expressing bacterial DNA topoisomerase I, RNA polymerase beta, beta' subunits via cloning and transformation.♣ Protein purification, in large scale, using affinity chromatography and size exclusion chromatography (AKTA FPLC).♣ Pull-down/Tandem Mass spectrometry approach for protein-protein interaction studies in bacteria.♣ Antibody purification from Rabbit serum for Co-Immunoprecipitation (Co-IP) assays/Tandem Mass spectrometry.♣ Antibiotic and oxidative stress challenge studies to investigate the significance of protein-protein interactions in Mycobacterium.♣ Helicase assays - Studied Putative helicases in Mycobacteria. ♣ Supervised undergraduate research projects♣ Assisted in editing and preparation of manuscripts for publication♣ Organized, maintained, and updated the lab’s website Show less

♣ Instructed General Chemistry I and II lab sessions♣ Conducted and graded lab examinations

♣ Assisted in designing the test material, and grading assignments♣ Tutored students in small groups or individually

♣ Research focused on Photodynamic therapy for skin cancer and photo-cytotoxic studies with Ruthenium complexes♣ DNA binding and cleavage studies, tissue culture♣ Responsible for recordkeeping and inventory in the lab