Design and characterization of synthetic nucleic acid nanostructures for programmable nanobiosensing applications- Developed a first-of-its kind demonstration of modular self-assembly of nanofibers using multiple, sequence-distinct peptide nucleic acids - a bio-orthogonal synthetic DNA mimic in organic solvent mixtures- Engineered micron-length, shape-changing DNA nanotubes using toehold-mediated strand-displacement mechanisms capable of acting as a fluoroscence-based active mechanosensor- Adept at working in a team as demonstrated through setting up a new lab, recruiting graduate students and initiating collaborations across different labs

Studying functional RNA for biophysical parameters and functionalized DNA for developing nanoscale structures- Synthesized novel branched DNA building blocks for control over junction angles in structured DNA nanotechnology-Synthesized functionalized DNA aptamers through chemical conjugation with gold nanoparticles, fluorophores,and polymers for cytochemical detection of acetylcholine ( a neurotransmitter)-Studied the folding pathway of TERRA RNA G-quadruplex using single-molecule optical tweezers to understand the biological role of intermediates in translation pathway-Identified and probed the structural bends and bulges in pri-miRNA to understand their role in recognition by Drosha/DGCR8 protein complex during biogenesis using single-molecule optical tweezers-Calculated the thermodynamic binding parameters of small molecules such as guanine and preQ1 in RNA riboswitches to understand the conformation switch that inhibit transcription and translation

Development of novel diagnostic tool using miRNA as biomarkers for kidney injury caused due to chemotherapy- Novel diagnostic method of fluorescently tagging miRNA in blood and urine samples to detect degree of kidney injury caused due to chemotherapy in cancer patients via a non-invasive approach

Supramolecular rheopectic gels as organic ferroelectrics-Assisted in the development of rheopectic gels using supramolecular interactions as organic ferroelectrics