Srishti Gurnani Email & Phone Number

Greater Boston Area

• Immunology Program
• Developed and optimized a cellular reporter-based on-target mechanistic assay that could detect bioactivity from fungal crude extracts. Delivered consistent, high-quality, reproducible cell data, aiding in the med-chem.
• Identified sensitivity limitations in the primary screening assay, driving a strategic shift to a secondary mechanistic assay for accurate efficacy determination and candidate nomination by the targeted deadline.
• Compiled… Show more Immunology Program
• Compiled comprehensive literature to inform and develop experimental designs for orthogonal measurements in “on-target” versus “off-target” cell lines to establish differentiation between SoC and our developmental.
• Developed and optimized mechanism of action studies ranging from nuclear translocation to multi-cytokine panel studies in PBMCs and whole blood for characterizing pre-candidates for nomination.

Greater Boston Area

• Integral part of the Biologics Discovery Research Group to develop a cutting edge method to combine insect cell and mammalian cell expression using a unique viral system
• Working with novel methods for optimizing protein expression in mammalian CHO cells and insect cell based baculovirus systems to increase productivity and decrease time needed to produce proteins of interest
• Developing a method to measure titer for biologics therapeutics and reagent properties as promising early… Show more
• Developing a method to measure titer for biologics therapeutics and reagent properties as promising early drug candidates Show less

Greater Boston Area

• Volunteered with the Drug Discovery group on campus and efficiently assisted postgraduatecandidates in conducting sterile and aseptic microbiology experiments.
• Completed assigned projects prior to due date with thorough research and understanding ofthe provided topic
• Followed health and safety procedures and regulations involved with sample and mediapreparation and general housekeeping for the lab

Mississauga, Ontario

• Successfully facilitated sample collection and processing, screening of study participants,and regulatory/ research documentation
• Proficiently performed dosing, sampling and completion of study conduct
• Accurately indexed, validated and recorded clinical data for study visits and reliablereferencing for all future studies
• Prepared comprehensive study documents, including study binder and protocol review forPhase II Human Clinical Trial Visits
• Effectively… Show more
• Effectively coordinated with Quality Assurance group in the development/ revision andimplementation of Standard Operating Procedures as required. Show less

Mississauga, Canada

• As a Scanner Specialist- Analyzed data from diary cards and determined study participants to be included/excluded based on the study-specific inclusion/exclusion criteria
• Assisted in maintenance and calibration of clinical, laboratory and EEC equipment
• Safely and efficiently processed blood, fecal, and urine samples from study participants
• Determined amount of pollen in Environmental Exposure Camber (EEC) by operating pollensamplers, staining pollen rods and examining… Show more
• Determined amount of pollen in Environmental Exposure Camber (EEC) by operating pollensamplers, staining pollen rods and examining pollen rods microscopically Show less

• Conducted Bioanalytical projects, sample preparation, laboratory procedures, maintained,calibrated and operated laboratory equipment in accordance with GLP guidelines
• Performed extraction and analysis of drugs/ metabolites from biological matrices, as inWatson LIMS, in compliance with GLP, SOP and regulatory guidelines
• Maintained project specific laboratory documentation (e.g. laboratory logbooks/ worksheets,analytical data, project notes/forms/memos) for assigned… Show more
• Maintained project specific laboratory documentation (e.g. laboratory logbooks/ worksheets,analytical data, project notes/forms/memos) for assigned projects and regulatory submissions Show less

Mississauga, Ontario

• Designed and conducted an experiment investigating starvation behavior in flies
• Part of the Fly-food making team and involved with general housekeeping for the lab

Toronto, Canada

• Handled ice-cream sales and managed cash collections at the Center of National Exhibition, Mississauga City Centre and the Toronto Rogers Cup at Rexall Centre

Toronto, Canada

• Supervised all areas of the Food and Beverage Dept., managed a staff of 20 people and provided high end customer service
• Reviewed inventory, assisted in set-ups and prepared daily cash reports

Doctor Of Philosophy - Phd, Molecular Pharmacology

Master Of Science (Ms), Biotechnology

Bachelor Of Science (Bsc), Molecular Biology