Sanne Martens-De Kemp Email & Phone Number

Netherlands

Rotterdam, South Holland, Netherlands

Amsterdam Area, Netherlands

Amsterdam Area, Netherlands

MiRacle is a FP7 EU project which focuses on the development of a therapeutic microRNA formulation for the treatment of head and neck cancer.

Amsterdam Area, Netherlands

Treatment options for squamous cell carcinomas in patients with Fanconi anemia (FA) are limited. We used a genome-wide siRNA library to identify genes that influence cell viability of tumors and preneoplastic lesions, but not the healthy mucosa in the oral cavity of FA patients.

Amsterdam Area, Netherlands

We used a genome-wide siRNA library to identify genes that influence cellular sensitivity to cisplatin in head and neck squamous cell carcinomas. In parallel we identified a novel membrane protein that is expressed by a small subpopulation of head and neck cancer cells that harbor cancer stem cell properties.I graduated in March 2014.

Amsterdam Area, Netherlands

An unselected population of young breast cancer patients (≤ 50 years of age) were tested for the presence of mutations in BRCA1 and BRCA2 and for the CHEK2*1100delC mutation, using DSDI (detection of small insertions and deletions), allelic discrimination and direct sequencing. The results were coupled to the tumour characteristics, tumour grading.

London, UK

An siRNA kinome library was employed to search for genes that influence tamoxifen sensitivity in breast cancer cells. One of these genes, CRK7, is not very well described in literature and therefore its role in sensitivity to the anti-oestrogen tamoxifen was determined. In parallel CDK10 was studied in the same experimental setup. (Carcinogenesis. 2009.

Msc, Oncology

Graduated as a Top Master student in Oncology. This study included an internship at the VU University Medical Center (Amsterdam, The.

Bas, Molecular Biology

Bachelor in Molecular Biology, including an internship at the Netherlands Cancer Institute (Amsterdam, The Netherlands).

Gymnasium