Stefano Jaconi Email & Phone Number
Who is Stefano Jaconi? Overview
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Stefano Jaconi is listed as C-suite, Founder and Managing Director at ONK OnlyNoseKnows AI-IT Biotech Consulting Company, a with 1 employees, based in Lugano Metropolitan Area, Switzerland. AeroLeads shows a matched LinkedIn profile for Stefano Jaconi.
Stefano Jaconi previously worked as CEO Founder at Swissbiotechsolutions Company Startup and Founder at Swissbiotechsolutions Company Startup. Stefano Jaconi holds Faculty Of Sciences – Biochemistry Master Studies from University Of Geneva.
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About Stefano Jaconi
Key achievements in Biotechnology and Pharma industry experience, specific tools and techniques, collaborative and leadership roles: • CMC Analytics Expertise: Led analytical method development and preclinical assessment of recombinant proteins and monoclonal antibodies (mAbs), focusing on the characterization and monitoring of Critical Quality Attributes (CQAs) using cutting-edge UHPLC/UPLC technologies. • Protein Engineering & Antibody Technologies: Designed and optimized recombinant proteins and therapeutic antibodies, leveraging rational design strategies to enhance functionality and developability. Proficient in antibody humanization, affinity maturation, and Fc engineering for improved efficacy. • Upstream and Downstream Processing: Extensive experience in scaling biomanufacturing processes for mAbs, including cell culture optimization (CHO/Sf9) and downstream purification techniques such as Protein A/G chromatography, ion-exchange chromatography, and size-exclusion chromatography (SEC). • Quality Control (QC) and Regulatory Compliance: Established and validated QC processes to ensure compliance with ICH guidelines and Good Manufacturing Practices (GMP) for preclinical and clinical biologics. • Preclinical Developability Assessment: Successfully conducted stability studies, aggregation analysis, glycosylation profiling, and immunogenicity prediction for mAbs in early-stage R&D pipelines. • Analytical Technologies: Advanced proficiency in mass spectrometry (MS), dynamic light scattering (DLS), capillary electrophoresis (CE), and peptide mapping, ensuring the comprehensive analysis of therapeutic proteins. • Collaborative Contributions: Played a pivotal role in cross-functional teams, bridging R&D, process development, and regulatory functions to accelerate project timelines and deliver high-quality therapeutic candidates. • Industry Leadership: Worked with leading Biopharma and Biotech companies, driving innovations in mAb discovery, production, and QC while maintaining an acute focus on patient safety and product integrity.https://www.ticinoscienza.ch/cerca.php
Stefano Jaconi's current company
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Stefano Jaconi work experience
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Ceo Founder
Current
Senior Research Associate
Downstream processing of recombinant monoclonal antibodies, QC and Developability assessment. Analysis of mAbs CQA by UHPLC.
Senior Research Associate
Senior Research Associate
Downstream processing of recombinant monoclonal antibodies, QC and Developability assessment. Analysis of mAbs CQA by UHPLC.
Biochemical Engineer Et
Technology Expert in cellular and molecular biology on a project entitled "Culture and characterisation of human mesangioblasts for the cell therapy of muscular dystrophy"
Laboratory Technician
Development technician on NGS (Next Generation Sequencing).Training of others Laboratory users of the PGM next-generation high throughput Sequencing System.
Technology Expert
R&D - New Biological Entities Technologies - Protein Engineering and Antibody Technologies (NBE-PEAT)• Implementation of Phage Display Technology Platform for generation of monoclonal Antibodies- Installation/operation & troubleshooting of core automated systems that support the antibody phage display 96/386-well screening platform- Execution of phage display hit discovery & affinity maturation campaigns including method validation/optimisation and assessment of new techniques when necessary- Multi-modal phage selections/panning using large scFv phagemids libraries against different target classes and in different formats- Elaboration, optimization/validation of associated HTS ELISA-based screening assays- Rearraying of scFv hit clone panels- Affinity ranking by Biacore 4000 (GE Healthcare) - Surface Plasmon Resonance (SPR)ligand-binding assay- Problems solving; giving recommendations for upgrades / system modifications.• Laboratory key responsibilities for the discovery and early optimization of antibody therapeuticdrug candidates• Quality Delegate (QD) for the Merck Serono Quality Management System (MS-QMS): Internal Dept. Auditor.• Write and revise Laboratory Standard Operating Procedures (SOPs)
Qms Qualified Person
Assistant Scientist
R&D Functional Genomics Department - Gene Discovery Group-Overall responsibility of the DNA Sequencing Service-Subcloning of Inpharmatica predicted genes by Gateway Technology and generation of expression clones for Bioprocessing Department and infection in FastTrack Proof-of-concept (POC) animal model
Senior Research Technician
R&D Functional Genomics Department - Gene Discovery Group-In charge of DNA Sequencing ServiceProteomics Signal Transduction Department-Gene cloning and Genotyping Analysis
Research Technician In Molecular Biology
Research on Hypoxia factors, proton channels, Ribozimes, differentiation of mouse embryonic stem cells.Responsible for the website of the Biology of Ageing Laboratory.
Research Technician In Molecular Biology
Research collaboration project on nicotinic acetylcholine receptor-related protein in human leukocytes purified from bone marrow issued from patients undergoing cardiac surgery.
Research Technician In Biochemistry
Research at Dermatology Department. Publications and Seminar on human serum retinol- binding protein.
Stefano Jaconi education
Faculty Of Sciences – Biochemistry Master Studies
Technician Et In Chemical Engineering, Chemical Engineering, Diploma
Bachelor Of Science - Bs, Biochemistry
Frequently asked questions about Stefano Jaconi
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What company does Stefano Jaconi work for?
Stefano Jaconi works for ONK OnlyNoseKnows AI-IT Biotech Consulting Company.
What is Stefano Jaconi's role at ONK OnlyNoseKnows AI-IT Biotech Consulting Company?
Stefano Jaconi is listed as C-suite, Founder and Managing Director at ONK OnlyNoseKnows AI-IT Biotech Consulting Company.
Where is Stefano Jaconi based?
Stefano Jaconi is based in Lugano Metropolitan Area, Switzerland while working with ONK OnlyNoseKnows AI-IT Biotech Consulting Company.
What companies has Stefano Jaconi worked for?
Stefano Jaconi has worked for Onk Onlynoseknows Ai-It Biotech Consulting Company, Swissbiotechsolutions Company Startup, Vir Biotechnology, Inc., Humabs Biomed, Subsidiary Of Vir Biotechnology, and Université De Genève - Faculty Of Medicine - Pathology And Immunology Department.
How can I contact Stefano Jaconi?
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What schools did Stefano Jaconi attend?
Stefano Jaconi holds Faculty Of Sciences – Biochemistry Master Studies from University Of Geneva.
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