Stephen Born Email & Phone Number

Woburn, Massachusetts, Us

• Develop new unit operations for the integrated continuous manufacturing of APIs• Apply data-driven strategies utilizing a plant-wide Quality by Design approach for the design and development of continuous API and drug product processes, including analytical methods and process controls, typically resulting in a 30-40% reduction in the COGS• Lead collaborative projects with pharmaceutical companies to convert their batch manufacturing processes to continuous

• Developed and patented new unit operations for the integrated continuous manufacturing of APIs, such as an engineered process bypass for membrane and clarification/polish filtration, a continuous rotary filter, and a continuous vacuum drum dryer

Cambridge, Ma, Us

• Served as the lead process chemist in the construction and operation of the Novartis-MIT Center for Continuous Manufacturing Red Line pilot plant, the first integrated continuous manufacturing system of its kind• Created a heterogeneous photocatalyst for the continuous production of singlet oxygen, and validated the process by meeting the industrial specifications of commercially available fragrance chemicals• Developed a safe, continuous pilot plant scale process for diphenylphosphoryl azide• Co-authored a book chapter on using continuous flow chemistry for fine chemicals and pharmaceuticals

Basel, Baselstadt, Ch

• Developed the chemistry and process to integrate a phase-transfer catalyzed reaction with liquid-liquid membrane separation to produce an API precursor

Berkeley, Ca, Us

• Designed and applied transition metal catalysis to the construction of the marine-derived steroid, Cortistatin A• Responsible for the development and scale-up validation of existing routes towards advanced intermediates leading to natural product target completion.

Ph.D., Organic Chemistry

Strategy And Innovation

B.S., Chemistry, Molecular Biology

Nsf Research Experience Program, Organometallic Chemistry Of Polymers