Stephen Doris

Stephen Doris Email and Phone Number

RNA Biology Scientist at Arrakis Therapeutics @ Arrakis Therapeutics
Stephen Doris's Location
Greater Boston, United States, United States
Stephen Doris's Contact Details

Stephen Doris personal email

n/a
About Stephen Doris

Comparative evolution is a powerful approach for understanding large biological data sets. During my PhD work, I used comparative evolution to identify RNA motifs within the core of the ribosome that are universally conserved or uniquely conserved in one phylogenetic domain of life (Bacteria, Archaea, or Eukarya). This work resulted in a provisional patent for novel drug targets. During my postdoctoral work at Harvard Medical School in Prof. Fred Winston’s lab, I investigated the information content of eukaryotic genomes, using yeast species as a model system. By integrating the most recent genomic methodologies, we discovered the existence of thousands of transcriptional promoters hidden within coding sequences (Doris, SM et al., Mol Cell, 2018). In optimal growth conditions these intragenic promoters remain dormant and thus have eluded prior detection. However, in the presence of genetic or environmental stresses, cells use these promoters to express alternative information, thereby expanding the coding potential of a single gene.

Stephen Doris's Current Company Details
Arrakis Therapeutics

Arrakis Therapeutics

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RNA Biology Scientist at Arrakis Therapeutics
Stephen Doris Work Experience Details
  • Arrakis Therapeutics
    Scientist Rna Biology
    Arrakis Therapeutics Feb 2019 - Present
    Waltham, Ma, Us
  • Harvard Medical School
    Postdoctoral Fellow
    Harvard Medical School 2010 - Dec 2017
    Boston, Ma, Us
  • Brown University
    Teaching Assistant
    Brown University 2004 - 2005
    Providence, Rhode Island, Us
    Medical Genetics for first year medical students. Course chair Al Dahlberg.
  • University Of Massachusetts Amherst
    Teaching Assistant
    University Of Massachusetts Amherst 1999 - 2001
    Amherst, Massachusetts, Us
    Advanced topics in Biochemistry. Course chair Robert Zimmermann
  • University Of Massachusetts Amherst
    Technician
    University Of Massachusetts Amherst 1998 - 1999
    Amherst, Massachusetts, Us
    Purification of nickel superoxide dismutase from anaerobic bacteria. Lab of Michael J. Maroney

Stephen Doris Skills

Biochemistry Cell Biology Western Blotting Genetics Molecular Biology Molecular Cloning Cell Sequencing Purification Pcr Protein Expression Protein Purification Qpcr Bioinformatics Immunoprecipitation Confocal Microscopy Gene Expression Yeast Molecular Genetics Genomics Research Cell Culture Microscopy Fluorescence Microscopy Life Sciences Polymerase Chain Reaction Rna Phylogenetics Laboratory Immunohistochemistry Immunofluorescence Lifesciences Real Time Polymerase Chain Reaction

Stephen Doris Education Details

  • Harvard Medical School
    Harvard Medical School
    Genetics And Genomics
  • Brown University
    Brown University
    Cell/Cellular And Molecular Biology
  • University Of Massachusetts Amherst
    University Of Massachusetts Amherst
    Biochemistry

Frequently Asked Questions about Stephen Doris

What company does Stephen Doris work for?

Stephen Doris works for Arrakis Therapeutics

What is Stephen Doris's role at the current company?

Stephen Doris's current role is RNA Biology Scientist at Arrakis Therapeutics.

What is Stephen Doris's email address?

Stephen Doris's email address is st****@****ard.edu

What schools did Stephen Doris attend?

Stephen Doris attended Harvard Medical School, Brown University, University Of Massachusetts Amherst.

What skills is Stephen Doris known for?

Stephen Doris has skills like Biochemistry, Cell Biology, Western Blotting, Genetics, Molecular Biology, Molecular Cloning, Cell, Sequencing, Purification, Pcr, Protein Expression, Protein Purification.

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