Stephen Thomson

Stephen Thomson Email and Phone Number

Ten63 Therapeutics @ Ten63 Therapeutics
Durham Fwy, Durham,North Carolina,United States
Stephen Thomson's Location
Durham, North Carolina, United States, United States
Stephen Thomson's Contact Details

Stephen Thomson personal email

About Stephen Thomson

I have extensive experience in drug discovery from target selection through clinical candidate selection and have also contributed to earlier clinical development teams through phase 1b studies. My experience includes working on and leading project and medicinal chemistry teams. My work has included several target types including ion channels, receptors, enzymes (kinase and non-kinase) and protein correction. I have worked closely across disciplines with biologists, screening technology (including DNA encoded libraries), DMPK, safety assessment (toxicology), chemical development, intellectual property and clinical to advance programs in both day-to-day operations as well as strategic planning. I am adaptive to new ideas and embrace new technologies, and will think outside the box to accomplish program goals. I have directly managed large medicinal chemistry teams and external chemistry CROs. I have also matrix managed cross-functional program teams through the drug discovery process. My goal is to discover top quality drug candidates for advancement to the clinic.

Stephen Thomson's Current Company Details
Ten63 Therapeutics

Ten63 Therapeutics

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Ten63 Therapeutics
Durham Fwy, Durham,North Carolina,United States
Employees:
26
Stephen Thomson Work Experience Details
  • Ten63 Therapeutics
    Scientific Advisor
    Ten63 Therapeutics Feb 2024 - Present
  • Ten63 Therapeutics
    Director Of Chemistry At Ten63 Therapeutics
    Ten63 Therapeutics Dec 2019 - Apr 2024
  • Thomson Medicinal Chemistry Llc
    Medicinal Chemistry Consultant
    Thomson Medicinal Chemistry Llc Aug 2019 - May 2023
    As Thomson Medicinal Chemistry LLC, I look to help companies and academic groups transform their ideas and vision into clinic candidates to treat disease and improve the life of patients. My experience and knowledge across the drugs discovery paradigm can be leverage to help you be successful in advancing your project through the discovery phase to the clinic.
  • Vertex Pharmaceuticals
    Research Fellow Ii
    Vertex Pharmaceuticals May 2015 - Jul 2019
    Boston, Ma, Us
    Project and chemistry leader for sodium channel inhibitor projects for the treatment of pain. Advance multiple compounds through lead optimization to clinical candidate selection. Project leader for hit to lead phase of alpha-1 antitrypsin (AAT) protein correction project for the treatment of alpha-1 antitrypsin deficiency (AATD). Experience in ion channel (sodium) inhibition, protein correction, and DNA encoded library (DEL) screening design, hit evaluation and follow-up.
  • Gsk
    Section Head, Medicinal Chemistry, Muscle Metabolism Dpu
    Gsk 2009 - Apr 2015
    Brentford, Middlesex, Gb
    Duchenne Muscular Dystrophy Drug discovery Program (2013-present)Co-program leader in the discovery of novel drug treatment for Duchenne Muscular Dystrophy. Selective Androgen Receptor Modulator Program (2009-2012)Chemistry sub-team leader in the discovery of novel selective androgen receptor modulators (SARM). Kv1.3 Inhibitor Program (2007-2009)Program leader in the discovery of Kv1.3 inhibitors for the treatment of type 1 and 2 diabetes, MS, and RA.
  • Gsk
    Section Head Medicinal Chemistry, Metabolic Diseases Center Of Excellence In Drug Discovery
    Gsk 2001 - 2008
    Brentford, Middlesex, Gb
    Glycogen Phosphorylase Inhibitor Program (2003-2009) Co-program leader in the discovery of novel inhibitors of Glycogen Phosphorylase for the treatment of type 2 diabetes. Led all aspects of the program from initial HTS through candidate selection. Member of clinical planning team (FTIH through Phase 2). Lead molecule completed phase 1B clinical studies. Glycogen Synthase Kinase 3 Inhibitor Program (2001-2003)Co-program leader in the discovery of inhibitors of GSK-3 for the treatment of type 2 diabetes.
  • Gsk
    Research Investigator
    Gsk 1988 - 2000
    Brentford, Middlesex, Gb
    KATP Channel Program (1997-2000)Co-program leader of a multidisciplinary research team in the discovery of KATP modulators for the treatment of diabetes and obesity. Glucose Sensitive Secretagogue Program (1995-1998)Co-program leader in the discovery of inhibitors of the pancreatic Kv2.1 ion channel for the treatment of diabetes. Peptide Nucleic Acids Project (1991-1995)Chemistry leader in the discovery of anti-sense agents for the treatment of cancer. Cardiovascular Research (1988-1991)Discovered novel oxathiazolones hypotension agents for the treatment of cardiovascular disease.

Stephen Thomson Skills

Drug Discovery Pharmaceutical Industry Medicinal Chemistry Drug Development Chemistry Life Sciences Organic Chemistry Biotechnology Clinical Development Pharmacology Organic Synthesis Biopharmaceuticals Analytical Chemistry Hplc Lifesciences Cross Functional Team Leadership Laboratory High Throughput Screening

Stephen Thomson Education Details

  • Stanford University
    Stanford University
    Organic Chemistry
  • San Diego State University
    San Diego State University
    Chemistry
  • San Diego State University
    San Diego State University
    Chemistry

Frequently Asked Questions about Stephen Thomson

What company does Stephen Thomson work for?

Stephen Thomson works for Ten63 Therapeutics

What is Stephen Thomson's role at the current company?

Stephen Thomson's current role is Ten63 Therapeutics.

What is Stephen Thomson's email address?

Stephen Thomson's email address is st****@****ail.com

What schools did Stephen Thomson attend?

Stephen Thomson attended Stanford University, San Diego State University, San Diego State University.

What skills is Stephen Thomson known for?

Stephen Thomson has skills like Drug Discovery, Pharmaceutical Industry, Medicinal Chemistry, Drug Development, Chemistry, Life Sciences, Organic Chemistry, Biotechnology, Clinical Development, Pharmacology, Organic Synthesis, Biopharmaceuticals.

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