Stephen Shang Email & Phone Number

• Led multiple integrative time-series imaging data projects.• Applied AI techniques in clinical decision analysis, resulting in peer-reviewed research submissions for decision support.• Developed scripts to address system issues.• Improved algorithms for data analysis, enhancing processing speed and accuracy.• Collaborated between software engineers, physicists, and clinicians to address a comprehensive variety of technical and clinical concerns.• Participated in professional and technical outreach at conferences and donor meetings.

Stanley Qi Lab

• Applied transcriptomics and ChIP-seq analysis to study newly discovered natural and synthetic CRISPR-Cas protein variants.• Cloned CRISPR variants to manipulate chromatin structure.• Performed Hi-C to analyze changes in chromatin interactions.• Conducted FRAP and imaging to study phase condensate dynamics of synthetic chromatin modifiers.

Charlottesville, Virginia Area

• Conducted integrative analyses combining transcriptomic and epigenomic data.• Led a multi-research group effort to use gene/epigenome editing and transcriptomic/epigenomic assays to investigate gene function related to drug resistance in vitro, in vivo, and in silico, leading to grants and publications.• Performed ChIP-seq to study transcription factor binding and gene regulation.• Collaborated on projects examining the effects of different treatments on multiple disease models.• Conducted single-cell RNA-seq to analyze cellular responses in cancer.• Developed computational algorithms for predicting cancer prognosis based on experimental data.

• Maintained mammalian cell cultures in the Burnett School of Biomedical Sciences.• Designed and tested DNA oligos for aptamer-based logic gates in the Department of Chemistry.• Learned atomic force microscopy to measure cell shear stress in the Department of Materials Science and Engineering.

Doctor Of Philosophy - Phd

Major: Molecular Biology And Microbiology/Biotechnology, Minor: Mathematics, Epigenomics And Crispr-Cas9

Activities and Societies: Chinese Asian Student Organization Treasurer 2006-2007