Stephen Shang Email & Phone Number

• Led multiple integrative time-series imaging data projects.
• Applied AI techniques in clinical decision analysis, resulting in peer-reviewed research submissions for decision support.
• Developed scripts to address system issues.
• Improved algorithms for data analysis, enhancing processing speed and accuracy.
• Collaborated between software engineers, physicists, and clinicians to address a comprehensive variety of technical and clinical concerns.
• Participated in professional and technical outreach at conferences and donor meetings.

Stanley Qi Lab

• Applied transcriptomics and ChIP-seq analysis to study newly discovered natural and synthetic CRISPR-Cas protein variants.
• Cloned CRISPR variants to manipulate chromatin structure.
• Performed Hi-C to analyze changes in chromatin interactions.
• Conducted FRAP and imaging to study phase condensate dynamics of synthetic chromatin modifiers.

Charlottesville, Virginia Area

• Conducted integrative analyses combining transcriptomic and epigenomic data.
• Led a multi-research group effort to use gene/epigenome editing and transcriptomic/epigenomic assays to investigate gene function related to drug resistance in vitro, in vivo, and in silico, leading to grants and.
• Performed ChIP-seq to study transcription factor binding and gene regulation.
• Collaborated on projects examining the effects of different treatments on multiple disease models.
• Conducted single-cell RNA-seq to analyze cellular responses in cancer.
• Developed computational algorithms for predicting cancer prognosis based on experimental data.

• Maintained mammalian cell cultures in the Burnett School of Biomedical Sciences.
• Designed and tested DNA oligos for aptamer-based logic gates in the Department of Chemistry.
• Learned atomic force microscopy to measure cell shear stress in the Department of Materials Science and Engineering.

Doctor Of Philosophy - Phd

Major: Molecular Biology And Microbiology/Biotechnology, Minor: Mathematics, Epigenomics And Crispr-Cas9

Activities and Societies: Chinese Asian Student Organization Treasurer 2006-2007