• Authoring regulatory filings, responding to health authority questions, and getting commercial approval.• Leading a team of scientists.• Downstream process development for capture through formulation (process characterization) for multiple mAbs (IgG1, IgG4).• Experience with development, scale-up, and improving product purifications for commercialization.• Involvement and leadership in cross-functional teams (CMC, technology development, department improvement and maintenance). Bridging gaps with Process Cell Culture, Analytical Biochemistry, Formulation Science, Scale-up, Clinical Manufacturing, Commercial Manufacturing, and Fit-to-Plant groups.• Development of tools to assess process risk and implement novel technologies, academic laboratory collaborations to validate scale-down models.• Strong professional writing and oral communication skills.• Analytical and preparative chromatography: Ion-exchange, mixed-mode, protein A, reversed-phase, size exclusion, immobilized metal-affinity, hydrophobic interaction, weak partitioning, capillary zone electrophoresis, membrane separations, etc.• Automation, JMP, and robotic high-throughput instrumentation expertise for DOE and QbD applications.

• Authoring regulatory filings, responding to health authority questions, and getting commercial approval.• Leading a team of scientists.• Downstream process development for capture through formulation (process characterization) for multiple mAbs (IgG1, IgG4).• Experience with development, scale-up, and improving product purifications for commercialization.• Involvement and leadership in cross-functional teams (CMC, technology development, department improvement and maintenance). Bridging gaps with Process Cell Culture, Analytical Biochemistry, Formulation Science, Scale-up, Clinical Manufacturing, Commercial Manufacturing, and Fit-to-Plant groups.• Development of tools to assess process risk and implement novel technologies, academic laboratory collaborations to validate scale-down models.• Strong professional writing and oral communication skills.• Analytical and preparative chromatography: Ion-exchange, mixed-mode, protein A, reversed-phase, size exclusion, immobilized metal-affinity, hydrophobic interaction, weak partitioning, capillary zone electrophoresis, membrane separations, etc.• Automation, JMP, and robotic high-throughput instrumentation expertise for DOE and QbD applications.

• Downstream process characterization.• Downstream process development (clarification through formulation), multiple mAbs (IgG1, IgG4).• Experience with development, scale-up, and improving product purifications for commercialization.• Involvement and leadership in cross-functional teams (CMC, technology development, department improvement and maintenance). Bridging gaps with Process Cell Culture, Analytical Biochemistry, Formulation Science, Scale-up, Clinical Manufacturing, Commercial Manufacturing, and Fit-to-Plant groups.• Development of tools to assess process risk and implement novel technologies, academic laboratory collaborations to validate scale-down models.• Strong professional writing and oral communication skills.• Pressure-flow relationship modeling across scales for compressible chromatographic gels.• Analytical and preparative chromatography: Ion-exchange, mixed-mode, protein A, reversed-phase, size exclusion, immobilized metal-affinity, hydrophobic interaction, weak partitioning, capillary zone electrophoresis, membrane separations, etc.• Automation, JMP, and robotic high-throughput instrumentation expertise for DOE and QbD applications.

• Downstream process development (clarification through formulation), multiple mAbs (IgG1, IgG4).• Experience with development, scale-up, and improving product purifications for commercialization.• Involvement and leadership in cross-functional teams (CMC, technology development, department improvement and maintenance). Bridging gaps with Process Cell Culture, Analytical Biochemistry, Formulation Science, Scale-up, Clinical Manufacturing, Commercial Manufacturing, and Fit-to-Plant groups.• Development of tools to assess process risk and implement novel technologies, academic laboratory collaborations to validate scale-down models.• Strong professional writing and oral communication skills.• Pressure-flow relationship modeling across scales for compressible chromatographic gels.• Analytical and preparative chromatography: Ion-exchange, mixed-mode, protein A, reversed-phase, size exclusion, immobilized metal-affinity, hydrophobic interaction, weak partitioning, capillary zone electrophoresis, membrane separations, etc.• Automation, JMP, and robotic high-throughput instrumentation expertise for DOE and QbD applications.

• Demonstrated the effects of displacement separations upon trace protein / peptide concentration and enrichment in ion-exchange separations, corroborated Steric Mass Action chromatographic column simulations performed.• Proof-of-concept protein / peptide displacement separations as a proteomic analysis platform.• Studied effects of carrier molecules upon displacement separations for improved trace protein concentration / enrichment.• Developed novel proteomic separation technique (ion-exchange displacement chromatography direct infusion mass spectrometry) for protein and peptide samples.• Characterization of proteins located in various prefractionation pools (trace proteins, homologous mutant library proteins expressed and purified, determination of protein-resin binding orientation for protein charge ladders).• Used E.coli culture lysates to obtain protein and peptide samples for novel proteomics separations.• Demonstrated differences between mass action and chemically selective displacers using nuclear magnetic resonance, chromatographic modeling, and column displacement experiments.• Developed weak partitioning chromatography project using Aspen Chrom. simulation platform.• Teaching assistant for undergraduate / graduate level biochemical engineering and separations classes. Duties included delivering lectures, leading problem solving sessions, office hours, and grading.

• Low temperature catalysis H2 production for fuel cells from renewable biomass resources. Powering fuel cells with CO via aqueous polyoxometalates and catalysts. Experimental and theoretical water-gas shift reaction kinetics.• Combinatorial, high-throughput screening methods for supported transition metal catalysts, microkinetic modeling, catalyst preparation and characterization techniques.

• Biomedical engineering of the respiratory system: mammalian cell culture techniques, antibody staining, two photon microscopy, obtained funding through grant writing, presented to colleagues, benefactors, peers.