Good Health was formed in 2009 by a group of physicians, researchers and venture capitalists with a shared interest in finding non-medical solutions for population health improvement through behavioral and dietary innovation. The company’s focus is on developing programs and products that are practical enough to gain consistent usage on a widespread basis. The company develops and licenses health-related technologies.

A concierge internal medicine practice

Restoration Foodworks is a venture-backed firm that partners with academia and enterprises to develop novel food technology and formulae. Areas of interest include high throughput screening to identify natural substances with desired molecular structure, testing of compound synergies and development of delivery systems to enhance bioavailability.

StayLo provides a best-in-class digestion modulator, offered as an OTC nutritional supplement. The bioactive ingredients in the supplement are extracted from the leaves of the white mulberry plant (Morus alba) through a proprietary extraction and standardization process. This process concentrates the bioactive iminosugars in mulberry leaves to ~8% of the total weight of the extract, which is approximately 50x greater than found in unprocessed mulberry leaves. Iminosugars in the supplement are sugar analogues similar in molecular structure to glucose. Taken orally, the iminosugars in the supplement act in the small intestine to temporarily bind enzymes that break down carbohydrates including starch, sucrose and other common sugars. This reversable, competitive inhibition of a-amylase, a-glucosidase and other carbohydrate-digesting enzymes results in a significant reduction in after-meal plasma glucose and insulin levels. The supplement’s mechanism of action is similar to that of the prescription drug Acarbose, except that ingestion of StayLo is not accompanied by the gastrointestinal distress that often accompanies the ingestion of Acarbose. In six clinical studies with healthy individuals the supplement has been demonstrated to reduce postprandial levels of both glucose and insulin by a mean of ~40%.