Early stage start-up developing products for the pharmaceutical and biotechnology industries.

Research and development live cell capture technology to serve the IVD oncology and prenatal diagnostics markets with next-gen sequencing of circulating tumor and fetal cells (CTC & CFC) collected from whole blood samples. Optimization of complex, competing variables in optical imaging fluorescence systems and related technologies. Responsible for system performance models, risk assessment and feasibility investigations of new system.Investigated advanced DNA library prep system using a new electrophoresis method, isotachophoresis. Working with a matrixed group of scientists and engineers, to develop an end to end workflow for next gen sample prep.

Design architect and project manager for the Illumina cBot instrument. This microfluidic system provides simplified, automated, sample prep for next gen sequencing using isothermal PCR DNA bridge amplification. Every sequencing run on HiSeq, Genome Analyzer, HiScanSQ, and HiSeq X Ten sequencers, is first processed on a cBot.Led the systems engineering team during the development of HiSeq and MiSeq sequencing systems. Direct and second tier manager for fully matrixed, multi-site engineering organization developing next generation HiSeq and MiSeq Sequencers.

Guided the systems engineering team during the development of multiple generations of patterned and bare wafer inspection products. Evaluated next generation technology proposals and optimized complex, competing variables in optical imaging modules to enhance wafer inspection systems. Responsible for system performance models, risk assessment and feasibility investigations of new proposed system architectures.Developed tool performance specifications, vendor selection criteria and established methods for subsystem components selection. Generated total system error budgets, cross talk, image computer loading and cost models. Determined laser scanning performance specifications and directed validation on first prototype tools.Direct reporting manager of team of senior engineers and project management for multiple development projects.