Bachelor in mechanical engineering, MScA in biomedical engineering, with a PhD in experimental medicine and a post-doctorate in biotechnology, cumulating 30 years of experience in the fields of regenerative medicine and biotechnology (author on over 50 scientific publications), as well as medical devices, where proficiency in project management of fundamental, pre-clinical, and clinical research was acquired. A strong experience as a Medical Science Liaison, involved in post-marketing studies, interacting with key opinion leaders, presenting key research results in international meetings, and conducting scientific training for field sales personnel. Also a strong background in design control, risk management, usability engineering and test verification/validation.Professional Achievements• Contributed to the development & FDA approval of ROSA surgical robot for total knee arthroplasty (TKA; 2019), partial knee arthroplasty (PKA; 2021), total hip arthroplasty (THA; 2021) and total shoulder arthroplasty (TSA) procedures (Zimmer CAS)• Contributed to BST-CarGel® (cartilage repair medical device) marketing approval in Europe (2012) and Canada (2014), and its acquisition by Smith & Nephew (2016)• Collaborated to the analysis and interpretation of BST-CarGel®’s randomized controlled trial at 5 years follow-up, and subsequent publication of the results• Supervision of cartilage repair case series and post-marketing studies• Management of a research team for the histological analysis of biopsies obtained during the clinical trial of BST-CarGel®• Upgrade of an academic laboratory to GLP standards• Speaker in many international scientific meetings on results of BST-CarGel®Academic Achievements• Specialized in preclinical studies and development of animal models• Co-author of a patent in Gene Therapy• Author/Co-author of 50+ scientific publications• Experienced presenter in national/international scientific meetings• Recipient of many scholarships of excellence• Supervisor of many graduate students • Best Master Thesis Award 1995-1996
Sm Bioexpert Consulting
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Independent ConsultantSm Bioexpert Consulting Mar 2024 - PresentMontreal, Quebec, CanadaConsulting in research and development in the field of medical devices, orthopedics, and regenerative medicine, offering 30 years of experience.
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Manager Clinical AffairsZimmer Biomet May 2019 - Mar 2024Montreal, Canada Area -
Lead ConsultantAmaris Sep 2017 - Apr 2019Montreal, Canada AreaDental Wings (10/2018-04/2019)Project: Development of a new dentistry laboratory scannerAchievement: Contributed to the verification & validation of production processes• Design Control (ISO 13485)• Agility Project Management• Test Verification/ValidationZimmer CAS (09/2017-10/2018)Project: ROSA Surgical Robot for Total Knee Arthroplasties (TKA)Achievement: Contributed to the development & FDA approval of ROSA Surgical Robot• Design Control (ISO 13485); User needs, Design inputs/outputs, Design review, Test verification & validation. • Usability Engineering (FDA, IEC 62366, ANSI HE75). • Clinical Evaluation Report (MEDDEV 2.7.1).• Risk Management (ISO 14971).• Agility Project Management• User Guide/Instruction For Use (IFU) writing. -
Sabbatical Year: Trip Around The WorldLife Experiences Jul 2016 - Jul 2017Spent an amazing year full of rich experiences while visiting 14 countries over 4 continents!!
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Medical Science Liaison (Europe)Smith & Nephew Jan 2016 - Jul 2016Calle Fructuos Gelabert 2, Sant Joan Despi, Barcelona, 08970, SpainRESPONSABILITIES- Product technology transfer from Piramal Life Sciences who sold the assets of BST-CarGel® to Smith & Nephew.- Perform training of S&N field sales personnel in all European countries for BST-CarGel® scientific background and hands-on preparation in surgery room.- Support S&N sales personnel in all European countries for visits and BST-CarGel® scientific presentations to KOLs.- Work with sales & marketing to maintain level of science in the multi-channel marketing strategy. -
Medical Science Liaison (Canada & Europe)Piramal Life Sciences, Bio-Orthopaedics Division Dec 2012 - Jan 2016475 Armand-Frappier, Laval, Qc, H7V 4B3, CanadaRESPONSABILITIES- Analysed results from an international GCP randomized controlled trial.- Supervision of case series and post-marketing studies for BST-CarGel®.- Engage with KOLs to identify areas of opportunities and competition. - Work with sales & marketing to maintain level of science in the multi-channel marketing strategy.- Presentation of key research results in national and international conferences, as well as supporting KOLs for their presentations.- Conduct on-going training of field sales personnel, as well as surgeons with presentations or the organization of cadaver laboratories. -
Advanced Research ManagerPiramal Life Sciences, Bio-Orthopaedics Division Sep 2010 - Dec 2012475 Armand-Frappier, Laval, Qc, H7V 4B3, CanadaRESPONSABILITIES- Management of preclinical and product-related research projects.- Supervision of biocompatibility tests performed for BST-CarGel®.- Supervision of histopathology work during preclinical and clinical phases.- Establish publication strategies for scientific results. -
Project Coordinator-Clinical Biopsy AnalysisBiosyntech Canada Inc. Jun 2008 - Sep 2010475 Armand-Frappier, Laval, Qc, H7V 4B3, CanadaRESPONSABILITIES- Management of a research team for the histological and microscopic analysis of repair tissue quality in osteochondral biopsies obtained during the BST-CarGel® clinical trial for cartilage repair in the femoral condyles.- Upgrade of an academic laboratory to GLP standards.- Development of procedures and protocols (SOPs) for the analysis of human tissue using various techniques.EXPERTISEGLP standards (Good Laboratory Practice), Histology, Immunohistochemistry, Polarized light microscopy (PLM), Electronic microscopy (ESEM), Histomorphometry, Assessment of cartilage quality. -
Product Manager-Bst-Cargel®/MeniscusBiosyntech Canada Inc. Aug 2007 - Sep 2010475 Armand-Frappier, Laval, Qc, H7V 4B3, CanadaPROJECTS- Meniscal wound healing using a glycerol phosphate-chitosan-blood implant.- Development of an in vivo non-viral gene delivery system using chitosan to help the regeneration of musculoskeletal tissues.EXPERTISEDevelopment of preclinical animal models (with GLP Standards), Animal surgery (rabbit, rat, mouse, sheep), Electronic microscopy (ESEM), Cell and molecular biology, Histology, Immunohistochemistry. -
Senior ScientistBiosyntech Canada Inc. Aug 2005 - Jul 2007475 Armand-Frappier, Laval, Qc, H7V 4B3, CanadaPROJECTS- Optimization of an in vitro non-viral gene delivery technique using chitosan.- Bone regeneration using a glycerol phosphate-chitosan-blood implant.EXPERTISEDevelopment of preclinical animal models (with GLP Standards), Animal surgery (rabbit, rat), Electronic Microscopy (ESEM), Cell and molecular biology, Histology, Immunohistochemistry. -
Postdoctoral Researcher, Canada Research Chair In Cartilage Tissue EngineeringPolytechnique Montréal May 2003 - Jul 20052900 Édouard-Montpetit, Montréal, Qc, H3T 1J4, CanadaPROJECT- Development of an in vitro non-viral gene delivery technique using chitosan.EXPERTISECell and molecular biology, Cell culture (primary cells and cell lines), Liquid chromatography (HPLC, SEC), Confocal microscopy (Zeiss), Flow cytometry (MoFlo, Cytomation), Elaboration of procedures and protocols under GLP standards. -
Doctoral Researcher, Laboratory Of Experimental Organogenesis, St-Sacrement HospitalUniversité Laval Sep 1997 - Aug 20021050 Chemin Sainte-Foy, Québec, Qc, G1S 4L8, CanadaTHESIS- The effects of an electric field on cutaneous wound healing using tissue-engineered constructs.EXPERTISEDevelopment of an in vitro tissue-engineered cutaneous wound healing model, Cell biology, Cell culture (fibroblasts, keratinocytes), Cell isolation, Histology, Immunohistochemistry, Electronic microscopy, Design of a medical research apparatus, Elaboration of procedures and protocols under GLP standards.
Stéphane Méthot Msc Phd Education Details
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Biotechnology -
Experimental Medecine -
Biomedical Engineering -
Mechanical Engineering
Frequently Asked Questions about Stéphane Méthot Msc Phd
What company does Stéphane Méthot Msc Phd work for?
Stéphane Méthot Msc Phd works for Sm Bioexpert Consulting
What is Stéphane Méthot Msc Phd's role at the current company?
Stéphane Méthot Msc Phd's current role is MScA Biomedical Engineering, PhD Experimental Medicine // Specialized in Medical Devices, Biotechnologies & Regenerative Medicine.
What schools did Stéphane Méthot Msc Phd attend?
Stéphane Méthot Msc Phd attended Université De Montréal - École Polytechnique De Montréal, Laval University, Université De Montréal - École Polytechnique De Montréal, Université De Montréal - École Polytechnique De Montréal.
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