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Subham Kumar Tripathy Email & Phone Number
Senior Research Fellow
at
Indian Institute of Technology, Bombay
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Role
Senior Research Fellow
Location
Mumbai, Maharashtra, India
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Subham Kumar Tripathy is listed as Senior Research Fellow at Indian Institute of Technology, Bombay, based in Mumbai, Maharashtra, India. AeroLeads shows a matched LinkedIn profile for Subham Kumar Tripathy.
Subham Kumar Tripathy previously worked as Technical Assistant in Confocal Microscopy at Indian Institute Of Technology, Bombay and Teaching Assistant : Introduction to Biology at Indian Institute Of Technology, Bombay. Subham Kumar Tripathy holds Doctor Of Philosophy - Phd, Biochemistry from Tata Institute Of Fundamental Research, Mumbai.
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Indian Institute of Technology, Bombay
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About Subham Kumar Tripathy
I'm currently pursuing R&D in therapeutics for hypertriglyceridemia, leveraging my expertise in liver biology and lipid metabolism. My background bridges interdisciplinary science with exposure to biochemistry and biophysics. My expertise includes conducting in vitro, tissue culture, and in vivo experiments, complemented by proficiency in various bioinformatic tools such as ImageJ for image analysis and Origin for data analysis. I am also skilled in using Microsoft Word, Excel, and PowerPoint for documentation and presentations. Additionally, I have expertise in confocal and fluorescence microscopy and experience with the basics of MD simulations.
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Indian Institute Of Technology, Bombay
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9 roles
Subham Kumar Tripathy work experience
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Senior Research Fellow
Kinesin Tail Domain (KTD): A Potential Therapeutic Candidate Against Hypertriglyceridemia | Thesis Supervisor: Prof. Roop MallikMy work explores the potential of targeting very low-density lipoproteins (VLDL) to effectively manage hypertriglyceridemia. I discovered that Kinesin-1, a motor protein, plays a crucial role in VLDL secretion by binding to triglyceride-rich lipid droplets (LDs) in the liver. Through all-atom molecular dynamics (MD) simulations, in vitro experiments, and cell culture assays, I demonstrated that the Kinesin-1 tail domain (KTD) preferentially binds to monolayer LD membranes. This binding disrupts LD distribution in hepatocytes and significantly reduces secreted TG levels without affecting other cellular functions. These findings highlight the potential of KTD as a therapeutic target to modulate lipid droplet dynamics and lower serum triglyceride levels, offering a promising alternative to current treatments. This research underscores the importance of innovative approaches in addressing complex metabolic disorders and advancing healthcare solutions.
Technical Assistant In Confocal Microscopy
As a dedicated Technical Assistant specializing in confocal microscopy, I excel in imaging a diverse range of biological and non-biological samples
Nov 2021 - Jun 2024
Teaching Assistant : Introduction To Biology
As a Teaching Assistant for the undergraduate course Introduction to Biology, I had the privilege of supporting and guiding students through the fundamental concepts of biology.
Nov 2022 - Mar 2023
Junior Research Fellow
Investigating Molecular Players at Lipid Droplet – Endoplasmic Reticulum Contact | Thesis Supervisor: Prof. Roop MallikI am passionate about exploring the intricate membranous network within cells, particularly focusing on the role of endoplasmic reticulum (ER) and membrane contact sites (MCSs) in cellular function and communication. My research expertise includes developing innovative in vitro assays to study MCSs, particularly between lipid droplets and ER and revealing dynamic changes influenced by metabolic states and immune activation. I have also investigated the regulatory roles of Rab18 GTPase and phosphatidic acid in MCS formation and function. Understanding these insights will contribute to address abnormal MCS formation and their implications in various disorders.
Aug 2018 - May 2021
Master Thesis Student
Structure-function relationship of Dengue replication complex proteins, NS2B and NS3 | Thesis Supervisor: Dr. Tirumala Kumar ChowdaryThe non-structural proteins form different dynamic interactions which aid in replication of Dengue virus. Non-structural protein 3(NS3) helps in the polyprotein processing by its N-terminal protease activity and the non-structural protein 2B(NS2B) acts as a cofactor for its protease activity. I am working to explore the details of NS2B-NS3 protein interaction at structural level.
Jul 2016 - May 2018
Summer Internship
Fabrication and Characterization of Chitosan-based Hydrogels | Supervisor: Dr. Yashveer SinghI worked on synthesizing hydrogels using biopolymers like chitosan, and xanthan gum. Also, did the characterization studies for swelling, degradation, self-healing, and visco-elasticity by Rheology.
May 2016 - Jul 2016
Summer Internship
Phage-Hunting for Mycobacterium smegmatis | Supervisor: Dr. Avinash SonawaneMy work was focused on isolating Mycobacteriophages against Mycobacterium smegmatis from various natural sources using the Phagehunting protocol, intending to explore their therapeutic potential against Tuberculosis.
May 2015 - Jul 2015
Summer Internship
Understanding the Transient Receptor Potential Vanilloid type 2 (TRPV2) and TRPV2 mediated neuritogenesis | Supervisor: Prof. Chandan GoswamiI investigated the interaction of TRPV2 protein with tubulin by MBP pull-down assay. I also analyzed TRPV2-mediated neuritogenesis in F11 cells
May 2014 - Jul 2014
5 education records
Subham Kumar Tripathy education
Doctor Of Philosophy - Phd, Biochemistry
Doctor Of Philosophy - Phd, Biosciences And Bioengineering
Master Of Science (5 Year Integrated), Life Sciences
Higher Secondary Education, +2 Science
Bjb Junior College - Bhubaneswar
Secondary Education, 10Th
Saraswati Sishu Vidya Mandir - Jajpur Town
FAQ
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What company does Subham Kumar Tripathy work for?
Subham Kumar Tripathy works for Indian Institute of Technology, Bombay.
What is Subham Kumar Tripathy's role at Indian Institute of Technology, Bombay?
Subham Kumar Tripathy is listed as Senior Research Fellow at Indian Institute of Technology, Bombay.
Where is Subham Kumar Tripathy based?
Subham Kumar Tripathy is based in Mumbai, Maharashtra, India while working with Indian Institute of Technology, Bombay.
What companies has Subham Kumar Tripathy worked for?
Subham Kumar Tripathy has worked for Indian Institute Of Technology, Bombay, Tata Institute Of Fundamental Research, Mumbai, National Institute Of Science Education And Research, Indian Institute Of Technology, Ropar, and Kiit School Of Biotechnology.
How can I contact Subham Kumar Tripathy?
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What schools did Subham Kumar Tripathy attend?
Subham Kumar Tripathy holds Doctor Of Philosophy - Phd, Biochemistry from Tata Institute Of Fundamental Research, Mumbai.
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