Sumitra Debina Mitra Email & Phone Number

Rotterdam, Zh, Nl

Netherlands

Partner with pharmaceutical companies to plan and execute various types of publications based on clinical trial data.

Netherlands

Engage ~20,000 followers across Twitter, LinkedIn, and Facebook by creating infographics and posts of published research from Pathogens & Disease

Co-reviewed journal articlesa. With Dr. Kimberly Kline (2016 -2018) – Scientific Reports, eLife, Infection and Immunityb. With Dr. Alan Hauser (2019 - 2021) – mBio, Lancet Infectious Diseases, Scientific Advances

Chicago, Illinois, United States

- Developed a protocol to visualize and enumerate type III secretion system needles on the surface of Pseudomonas aeruginosa. This helped us correlate the T3SS to P. aeruginosa cytotoxicity levels.- Developed a novel protocol to produce P. aeruginosa minicells for cryoEM.- Co-developed the Galleria mellonella high-throughput model to assay P. aeruginosa virulence.- Co-discovered a novel Pseudomonas species highly resistant to hygromycin.

Singapore

Dissertation: The role of sequence elements and protein interactions in focal subcellular localization of Sortase A in Enterococcus faecalis- Identified that sequence elements, individually, play a small role in SrtA localization to distinct foci in E. faecalis.- Identified FtsY and DnaK as protein interacting partners of SrtA. DnaK plays a possible role in localizing SrtA to the septum. This work constitutes the first mechanistic insight into how SrtA localizes to discrete foci in any gram-positive bacterium.

Mahim West

- Collected clinical carbapenem-resistant Enterobacteriaceae to evaluate the CarbaNP test for carbapenemase detection.- Evaluated the prevalence of antibiotic resistance of clinical Helicobacter pylori strains by E-test and its association to infection eradication in patients.

Navy Nagar

Dissertation: Towards understanding the role of novel genes involved in yeast PHO pathway Constructed five deletion strains of genes hypothesized to play a role in the yeast phosphate-signaling (PHO) pathway and analyzed their deletion effect on the PHO pathway by a colorimetric assay measuring the activity of the extracellular phosphatase enzyme.

Mumbai, Maharashtra, India

Project topic: Determination of total urinary protein laboratory reference range for high urine volume- Analyzed data from 1820 patients to determine the correlation between urine volume and total urinary protein.- Established a new reference range for the hospital for healthy patients and nephropathy patients with higher urine output.

Mumbai, Maharashtra, India

Honor’s project: Isolation and characterization of engine oil degrading microorganisms from Mithi river, Mumbai- Enriched for bacteria that degrade engine oil, a major pollutant of the Mithi river in Mumbai.- Characterized the consortia of isolates with different sources of nitrogen and phosphorus, pH, temperature and engine oil concentrations. We determined growth yield by chloroform extraction.- Growth in urea and ammonium phosphate at pH 7 is ideal for degrading <10% v/v engine oil.

Medical Microbiology And Bacteriology

Activities and Societies: Biology Graduate Student Club, Hon. Secretary

Master'S Degree, Biotechnology, Distinction

Activities and Societies: Chairperson of Intercollege Biotechnology fest 'Palindrome' in 2010.

Bachelor'S Degree, Biotechnology, Distinction

Activities and Societies: Science Honor's Program

Education record

Activities and Societies: Drama team and the school choir