Sunny Trivedi

Sunny Trivedi Email and Phone Number

Skilled Protein Biochemist | Cell and Molecular Biologist | Spatial Biologist @ Bruker Spatial Biology
Sunny Trivedi's Location
Menlo Park, California, United States, United States
Sunny Trivedi's Contact Details

Sunny Trivedi work email

Sunny Trivedi personal email

n/a
About Sunny Trivedi

With over a decade of research experience in biomarker discovery, assay development, protein biochemistry, immunohistochemistry, and downstream processing, I am a self-driven molecular biologist. My result-oriented approach has been sharpened through 3 years of industrial experience and successfully managing a customer-facing self-owned business for one year. The academic and industrial settings have cultivated valuable qualities in me, including strong interpersonal skills, a knack for troubleshooting, and unwavering persistence.During my tenure at Akoya, I diligently pursued the application of cutting-edge techniques and the integration of multi-omics data to catalyze advancements in drug discovery and precision medicine. In a remarkably short period of only two years, I played an instrumental role in the development of chemistries capable of detecting over 100 proteins and RNAs on a single cancer tissue section, exhibiting unprecedented levels of sensitivity and specificity. This achievement necessitated the optimization of microfluidic patterns, the meticulous troubleshooting of the detection algorithm, and fruitful collaborations with other industry-leading organizations to realize a truly comprehensive multi-omic bioassay.During my Ph.D., I focused on characterizing Mindbomb2 (Mib2), an E3 ubiquitin ligase, as a regulator of collective cell migration, a principal phenomenon for cancer metastasis. Through my research, I demonstrated that Mib2 regulates the Jak/Stat signaling pathway and stabilizes cytoskeletal proteins to govern the active migration of border cells in Drosophila ovaries. In addition, I collaborated with four cross-functional multidisciplinary teams to investigate the role of microRNAs in collective migration.Our findings on the role of Jak/Stat signaling in the regulation and relevance of human cancer and metastasis were published in a widely acclaimed review article, garnering over 60 citations in just two years. Throughout my career, I have honed my scientific writing skills, resulting in three travel grants, two NIH research grants, 15+ international presentations, and reviewing five research articles for journals. Aditionally, I have had the privilege of instructing over 500 students and mentoring three graduate students and nine undergraduate students during my Ph.D.Beyond the lab, I am a table tennis enthusiast and a bakery business owner with a flair for designing cakes. I also strongly believe in the importance of science advocacy and aspire to be an ambassador of science for young minds.

Sunny Trivedi's Current Company Details
Bruker Spatial Biology

Bruker Spatial Biology

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Skilled Protein Biochemist | Cell and Molecular Biologist | Spatial Biologist
Sunny Trivedi Work Experience Details
  • Bruker Spatial Biology
    Senior Scientist
    Bruker Spatial Biology Aug 2023 - Present
    San Jose, California, United States
  • Akoya Biosciences, Inc.
    Project Lead
    Akoya Biosciences, Inc. Aug 2022 - Aug 2023
    Menlo Park, California, United States
    • Led a team of brilliant minds to realize the true potential of PenocyclerTM Fusion by achieving high plex detection of both protein and RNA on same tissue section.• Developed a robust and true multiomics chemistry by spatial phenotyping 46 samples, 23 tissue types, and more than a million cells that can provide an accurate picture of tumor progression and response to therapy.
  • Akoya Biosciences, Inc.
    Scientist 1
    Akoya Biosciences, Inc. Nov 2021 - Jun 2023
    Menlo Park, California, United States
    • Spearheaded the development of a novel in-situ RNA detection assay that can accurately and efficiently detect 100+ RNA targets on single tissue section.• Contributed extensively to the refinement and optimization of the assay, continually enhancing the protocol to ensure optimal performance across a wide array of experimental conditions and diverse tissue contexts.• Identified and optimized key parameters pertaining to the assay detection such as microfluidics, target panel design… Show more • Spearheaded the development of a novel in-situ RNA detection assay that can accurately and efficiently detect 100+ RNA targets on single tissue section.• Contributed extensively to the refinement and optimization of the assay, continually enhancing the protocol to ensure optimal performance across a wide array of experimental conditions and diverse tissue contexts.• Identified and optimized key parameters pertaining to the assay detection such as microfluidics, target panel design, and quantification pipeline. Show less
  • University Of Maryland Baltimore County
    Doctoral Research Assistant
    University Of Maryland Baltimore County Aug 2015 - Oct 2021
    Maryland, United States
    • Leveraged immuno-histochemistry to unveil novel roles for E3 ubiquitin ligase in collective cell migration using insect cells and whole tissue samples.• Created temperature-sensitive mosaic mutant clones to study genetic variations in cellular functions.• Employed mass spectrometry to identify and characterize novel protein targets, shedding light on their involvement in disease pathology.• Utilized confocal microscopy techniques to analyze migration profiles and cellular behavior… Show more • Leveraged immuno-histochemistry to unveil novel roles for E3 ubiquitin ligase in collective cell migration using insect cells and whole tissue samples.• Created temperature-sensitive mosaic mutant clones to study genetic variations in cellular functions.• Employed mass spectrometry to identify and characterize novel protein targets, shedding light on their involvement in disease pathology.• Utilized confocal microscopy techniques to analyze migration profiles and cellular behavior in response to external stimuli, and protein re-distribution in the extracellular space of live whole tissue.• Exploited molecular biology techniques to unveil the impact of microRNAs on cell migration. Show less
  • University Of Maryland Baltimore County
    Graduate Teaching Assistant
    University Of Maryland Baltimore County Aug 2015 - Oct 2021
    Maryland, United States
    • Experimental Biology Lab (Demonstrated experimental protocols, quizzed, and led discussions)• Human Anatomy and Physiology Lab (Taught and demonstrated cat muscle dissections)• Molecular Genetics Lecture (Quizzed, led discussions, and designed exams)
  • Bakesters
    Co-Founder And Creative Partner
    Bakesters Jul 2014 - Jul 2015
    Ahmedabad, Gujarat, India
    Responsible for effectively transforming a home baking business into a successful pastry bakery. Acquired the ability to negotiate and close sales, conflict resolution, and customer management skills by dealing with 1000+ customers by meeting assigned targets, assisting with sales calls, and providing product support.
  • Intas Pharmaceuticals Ltd. (Biopharma Division)
    Research Assistant
    Intas Pharmaceuticals Ltd. (Biopharma Division) Nov 2014 - Apr 2015
    Ahmedabad, Gujarat, India
    • Performed bioassays on NHL patient samples and assessed their efficacy and potency on cancer cell lines• Optimized and carried out toxicity assays (ADCC and CDC) to check the potency of proposed biosimilar drugs• Led a team of trainees to maintain cell lines and perform in silico analysis
  • Advanced Centre For Treatment, Research And Education In Cancer(Actrec)
    Research Trainee
    Advanced Centre For Treatment, Research And Education In Cancer(Actrec) Jun 2013 - May 2014
    Mumbai, Maharashtra, India
    • Discovered crucial amino acids essential for the protease activity of mitochondrial protease, HtrA2. Engineered mutants through site-directed mutagenesis, successfully purified proteins in bacteria, and meticulously characterized their activity using in vitro protease assays.• Applied analytical and biophysical techniques to monitor protein conformation and stability, ensuring an accurate assessment of its functional properties.
  • Cadila Pharmaceuticals Limited
    Research Intern
    Cadila Pharmaceuticals Limited Mar 2012 - Jun 2012
    Ahmedabad Area, India
    • Explored drug QC, Formulations, Microbiological testing, GLP and Pathogenicity

Sunny Trivedi Skills

Chromatography Human Cell Lines Site Directed Mutagenesis Reverse Transcription Polymerase Chain Reaction Ion Exchange Transfection Western Blotting Gel Electrophoresis Microscopy Protien Biology Protein Structure Confocal Microscopy Assay Development In Situ Hybridization Immunofluorescence Rna Biology Cell Culture Protein Engineering High Performance Liquid Chromatography Purification Drosophila Rna Isolation Protein Crystallization Developmental Biology Molecular Biology Polymerase Chain Reaction Dna And Rna Biology Real Time Polymerase Chain Reaction Bioassay Sequencing Sds Page Molecular Genetics Biophysics Protein Assays X Ray Crystallography Mammalian Cell Culture Immunoprecipitation Molecular Cloning Protein Expression Protein Purification Dissection Chip Seq Protein Characterization Biochemistry Dna Extraction Project Management Dna Sequencing Fluorescence Microscopy Structural Biology Protein Chemistry

Sunny Trivedi Education Details

Frequently Asked Questions about Sunny Trivedi

What company does Sunny Trivedi work for?

Sunny Trivedi works for Bruker Spatial Biology

What is Sunny Trivedi's role at the current company?

Sunny Trivedi's current role is Skilled Protein Biochemist | Cell and Molecular Biologist | Spatial Biologist.

What is Sunny Trivedi's email address?

Sunny Trivedi's email address is st****@****bio.com

What schools did Sunny Trivedi attend?

Sunny Trivedi attended University Of Maryland Baltimore County, University Of Maryland Baltimore County, Sardar Patel University.

What skills is Sunny Trivedi known for?

Sunny Trivedi has skills like Chromatography, Human Cell Lines, Site Directed Mutagenesis, Reverse Transcription Polymerase Chain Reaction, Ion Exchange, Transfection, Western Blotting, Gel Electrophoresis, Microscopy, Protien Biology, Protein Structure, Confocal Microscopy.

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