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Synthetic organic chemist with more than 41 years of extensive experience in the pharmaceutical industry designing and synthesizing a wide variety of diverse chemical compounds. Utilized literature methods to determine best synthetic route and employed chromatographic and spectroscopic methods for purification and characterization. Well organized, careful and thorough chemist, good team player, committed to getting the job done and meeting project deadlines. Specialties: Medicinal ChemistryOrganic Chemistry
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Research AssociateMerck 1992 - 2009Extensive experience utilizing medicinal chemistry skills to identify and optimize lead structures aimed at producing clinical candidates for anti-hypertensive, antimicrobial, cholesterol lowering, metabolic syndrome and anti-diabetes projects. -
Research ChemistMerck Jan 1967 - Jan 1992Extensive experience utilizing medicinal chemistry skills to identify and optimize lead structures aimed at producing clinical candidates for anti-hypertensive, antimicrobial, cholesterol lowering, metabolic syndrome and anti-diabetes projects.Designed and synthesized compounds from many structural classes - cyclic, open-chain, heterocylic, steroids, peptides, nucleotides.Reviewed biological data to create and synthesize structural modifications needed to increase biological activity.Maximized biological potency by altering polar, steric and electronic characteristics of research molecules.Optimized conditions for increased yields and ease of purification for many synthetic schemes.Experience with reactions of <5 mg to > 100g.Discovered, isolated and characterized a 4% impurity responsible for the observed activity in a test compound resulting in a new lead.Utilized libraries of reactants to run parallel syntheses.
Susan Aster Skills
Susan Aster Education Details
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Boston UniversityOrganic Chemistry -
City University Of New York-Brooklyn CollegeChemistry
Frequently Asked Questions about Susan Aster
What is Susan Aster's role at the current company?
Susan Aster's current role is Research Associate, Medicinal Chemistry.
What is Susan Aster's email address?
Susan Aster's email address is sd****@****ine.net
What schools did Susan Aster attend?
Susan Aster attended Boston University, City University Of New York-Brooklyn College.
What skills is Susan Aster known for?
Susan Aster has skills like Medicinal Chemistry, Organic Synthesis, Organic Chemistry, Chromatography, Hplc, Purification, Pharmaceutical Industry, Lc Ms.
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