Susan E. Bolin, Dvm, Phd Email & Phone Number

North Chicago, Illinois, US

Provide veterinary support / oversight for pre-clinical drug discovery research efforts with emphasis in oncology, dermatology, safety pharmacology and translational science / imaging.

Provided veterinary and program oversight for oncology related studies. Directed program toward achieving AAALAC accreditation.

Indianapolis, IN, US

Oncology and Animal Health and Welfare Expert Consultant

• Responsibilities:Managed 15,000 sq ft animal facility with a $3.5M operating budget; Experience with housing and veterinary care of rodents, NHP's, Beagle dogs and companion animals.Selected Accomplishments:
• Managed a team of eight laboratory animal technicians working with immune-competent and – deficient rodents
• Coordinated all program efforts around first round AAALAC accreditation achievement in February 2010
• Maintained controlled substance inventory for BRF complying with all DEA regulations

• Responsibilities:Oversaw and coordinated activities such as meeting organization, facility inspections, assigning designated reviewers, providing training materials and updating the Institutional OfficialSelected.
• Coordinated the update, review and writing of animal care and use protocols
• Guided organization on protocols involving the potential for pain or distress to ensure compliance with animal welfare standards including the Guide for the Care and Use of Laboratory Animals including 3 R’s; close.
• Complied with USDA regulations for covered species

• Responsibilities:Managed team of 5 biologists (2 MS, 3 BS) supporting 12 different projects and programs; directly supported 6 compounds that achieved IND status. Designed and coordinated in vitro and in vivo studies.
• Directly supported the development of six compounds that achieved IND status and six new therapeutic agents in oncology pipeline
• Developed and validated orthotopic tumor models using human and murine cell lines for multiple cancers
• Consistently exceeded performance standards by exceeding timelines and achieving outlined goals and objectives; effectively managed changes in goals and objectives for self and team
• Able to critically evaluate relevant literature and clinical data and apply this knowledge to research efforts; directly involved in team discussions to determine pre-clinical models to use in support of clinical.

Albuquerque, NM, US

• Selected Accomplishments:
• Performed transient and stable mammalian cellular transfections, molecular cloning, and flow cytometry
• Assisted in the development of a rat model of human pancreatic carcinoma for evaluation of anti-somatostatin analog therapies
• Conducted high throughput screening, molecular cloning and sequencing including computer data analysis, colony lifts, library expression analysis and screening, oligonucleotide design and synthesis
• Performed transient and stable mammalian cellular transfections, molecular cloning, and flow cytometry. Assisted in development of a rat model of human pancreatic carcinoma for evaluation of anti-somatostatin analog.

• Selected Accomplishments:
• Dissertation research involved identification of susceptibility markers in murine lung cancer to understand cancer susceptibility differences in people
• Studied K-ras gene expression in alveolar type II cells using molecular techniques including Northern, Southern and Western analyses
• Performed bronchoalveolar lavage and pulmonary antigen instillation on dogs and monkeys to determine age-related effects on serum antibody production (ELISA); Assisted with lung transplant surgeries in Beagle dogs
• Diagnosed and treated research Beagle dogs and NHP’s (macaques) maintaining animal health and welfare

Ph.D., Cancer Biology

Dvm Residency / Ph.D Program, Combined Small Animal Oncology Residency / Cancer Biology Coursework

D.V.M., Small Animal Medicine