Swapnil Chavan Email & Phone Number

Sweden

Orebro, Sweden

-Established a high content imaging based chemical risk assessment project from scratch.-Analyzed lipidomics, medical imaging, and clinical data for psychosis disorder.

Raleigh-Durham, North Carolina Area

-Developed a read-across approach using structural, physchem, metabolic, toxicokinetics, in vitro and in vivo study data.-Developed functions and workflows for transcriptomics data analysis, gene set enrichment and pathway analysis.-Design and developed database for regional screening levels.-Identified structure, metabolic and bio-activity similarity based analogs for the reference chemicals that are being used in two leading research projects

Sweden

-Developed a global QSAR model for acute toxicity -Developed a classification model for hERG k+ channel derived toxicity.-Predicted chronic toxicity with support of acute toxicity data by means of k-NN classification and read-across approach.-Taught MSc students the subject of Chemometrics.-Published 3 scientific papers.

Munich Area, Germany

Constructed different machine learning models for prediction of hERG k+ channel derived toxicity. The outcome of this research was published in reputed journal.

-Identified hits for different targets (for Cancer, Influenza), and derived ligand based quantitative SAR.-Further lead optimization of identified hits by structure based and ligand based drug designing approaches.

Doctor Of Philosophy (Ph.D.), Chemistry

PhD Thesis title: Towards new computational tools for predicting toxicity. Courses: Research methodology, Laboratory safety.

Master Of Science (M.S.), Pharmacoinformatics, 8.3/10

Thesis title: Mapping the binding site of TAK-779 compound in C-C chemokine receptor 2b by alanine-scanning mutagenesis: Free energy.

Bachelor Of Pharmacy (B.Pharm.), Pharmacy, First Class With Distinction

Courses: Pharmaceutics, Pharmacology, Pharmaceutical analysis, Medicinal chemistry, Pharmacognosy, Microbiology, Biopharmaceutics