 Developed several high throughput GC screening methods for various bioproducts Programmed automation methods for sample preparation, screening and DOE experiments Developed of UV spec assay for detection of aldehydes and ketones in product Investigated out of spec results for extraction method and recommended changes for improvements Developed a robust sample extraction method and ISTD GC method to improve method precision Coordinated release of new method to different competency groups including fermentation and process development Developed and qualified GC-FID ‘odor’ method for stability study support Performed routine testing in support of stability studies Assisted in maintaining high safety scores for laboratory inspections Received two ‘spot bonuses’ for going above and beyond the call of duty

 Collaborated with cross-functional groups to create robust protocols for efficient screening of yeast strains evolved for improved cellulosic Biofuel production.  Developed a fast and robust HPLC screening method that increased sample throughput 3 fold.  Supported strain characterization fermentation process development scale-up and scale-down. Introduced an improved HPLC method to identify ancillary carbohydrates to more accurately determine key performance indicators (KPI). Initiated use of certified check standards and standard operating procedures (SOPs) for data consistency and integrity. Coordinated and led department wide chemical inventory: consult with EH&S, train group on proper procedures and QC data input.  Independently researched and developed high throughput screen (HTS) for intra-cellular metabolites. Utilized Design of Experiments (DOE) software to investigate ideal assay conditions. Programmed and optimized automation methods for sample preparation, screening and DOE.  Accelerated improvement and standardization of analytical data reporting from integration to simplified uploads to LIMS and automated calibrations. Managed supply, storage and use of certified check standards. Created poster on importance of analytical method validation/qualification in R&D. Acted as liaison for several cross-functional groups and was responsible for maintenance, troubleshooting, repairs and management of instrument allocation for up to 10 machines. Achieved and maintained high weekly HPLC sample throughput with decreased downtime.  Introduced Excel based macro to consolidate large amounts of fermentation data.  Initiated and created HPLC training presentations and documents across multiple departments. Participated in formal process safety reviews for chemical safety and waste stream management. Received 3 employee recognition awards including one for “Excellent collaboration between groups and ability to speed up processes.”

 Competent in all areas of small molecule analytical development. Performed analytical testing of small molecule active pharmaceutical ingredients (API) including determination of assay, Karl Fischer, dissolution, ion chromatography and residual solvents. Responsible for GMP drug substances lot release testing and wrote Certificates of Analysis. Developed and optimized analytical methods and performed necessary validation experiments. Provided input for development documents such as technical transfer reports, development reports, validation reports, SOPs, INDs, etc.  Performed testing of degradation products in support of GMP stability studies. Coordinated with contract labs for various USP tests. Consistently communicated analytical results at interdepartmental project team meetings.  Attended training in order to develop and present a Waters® HPLC maintenance guideline for the entire Analytical Development department. Provided editorial review of test methods and acted as laboratory resource for junior/new employees.  Trained new and existing analysts on SOP’s and analytical techniques and wrote training modules.

 Collaborated with fellow analysts to run EPA methods 624, 524.2 and 8260 in a high throughput testing laboratory. Responsible to maintain, calibrate, troubleshoot and repair several HP GC/MS systems. Collected, evaluated and reported data in a timely and accurate manner using LIMS system. Self-sufficient and diligent as a lone second-shift analyst.