Member of leadership team. Built disruptive start-up via a global network of biopharma experts & novel processes, harnessing forecasting science to predict clinical trial outcomes.• Integrated strategy and tactics to lead operations including priorities, pace & execution.• Designed and built processes & culture to drive company productivity.• Recruited, hired, onboarded business-critical team members from entry level to MDs.• Reviewed dozens of clinical trial research reports; moderated live science discussions.• Managed remote reports (MBAs, PhDs, PharmDs), incl. hiring, deliverables, exiting.• Ran internal comms; assisted in external outreach, fundraising & investor relations.• Our method predicted outcomes of over 60 clinical trials with unprecedented accuracy.

Founded, built, and sold a management consulting practice to improve workforce performance.• Advised, coached, gave workshops to improve engagement, productivity, retention.• Performed tactical and strategic research to define business model and client profiles.• Arranged & led meetings, managed projects to deliver results for clients & collaborators. • Directed business operations, including legal and financial logistics.• Authored & provided HCRI- and SHRM-approved HR continuing education.

Led teams and directed projects to create scientific solutions across multiple therapeutic areas.• Drove scientific business development to close dozens of contracts worth > $3 million.• Designed & directed cell, protein and nucleic acid testing of small & large molecule drugs.• Developed, managed novel strategy to keep FDA approval for $25M/yr children’s medicine. • Managed direct reports: hired, coached, exited, promoted staff in 30-person matrix group.• Reviewed and contributed to financial forecasts; troubleshot processes (FMEA & RCA). • Directed projects, improved staff performance, certified as Lean Six Sigma Yellow Belt.• Initiated and coordinated dozens of employee engagement efforts and trainings.• Authored, reviewed protocols & reports for GMP-compliant projects; site Biosafety Officer.

Created and led teams to validate targets, improve safety and advance drug discovery.• Built and led multiple international cross-functional project teams.• Led global R&D Reward and Recognition Team to improve employee retention.• Served on GSK Strategy and Portfolio Team to craft strategic R&D plans.• Worked on global R&D People Strategy Team to create new company policies.• Received multiple awards, Exceptional Science Award, initiated creativity workshops.• Designed, ran and supervised large cell-based assays for oncology indications.• Identified iPS-cardiomyocyte transcriptomic toxicity signatures for compound safety.• Industrialized Connectivity Mapping for Systematic Drug Repurposing project.• Created transcriptional assay to advance Cartilage Regeneration program.• Built new assays (acetylation, methylation) to enable Epigenetic Modulation initiative. • Validated targets via SILAC chemoproteomics for HDAC & malaria projects.

Developed molecular, cell culture and protein technologies for therapeutic proteins.• Coordinated projects to enable development of new recombinant therapeutics. • Negotiated, managed external collaborations. • Received achievement award; GXP certified; lab safety officer.• Initiated new technology efforts, e.g. qPCR, PCR-fingerprints, Southerns, high-res Westerns.

Optimized molecular biology techniques to industrialize new drug-discovery platform at start-up.• Built T7 phage display libraries; cloned hundreds of PCR products in parallel.

Created peptide-based delivery systems to bridge biological and synthetic materials; start-up.• Initiated and led internal and external projects, including bone regeneration & antimicrobials. • Edited two SBIR grants, resource on another three, co-inventor on four patents. • Gained unique start-up experience as first bench scientist hired.• Built company’s business-critical molecular biology infrastructure. • Designed multiple assays including ELISA, FACS, in vitro and in vivo models.

Discovered novel drug leads for antimicrobials and nuclear receptor modulation.• Led several project teams to success. Co-authored grant, 4 papers. Supervised staff.• Taught cloning, built & used phage display libraries, purified proteins.• Formatted, ran high-throughput screens (TRF, FP, FRET, extensive automation).

Discovered novel drug leads for antimicrobials and nuclear receptor modulation; start-up.• Built promoter/reporter constructs, cloned genes.• Purified proteins via affinity, size exclusion, and ion-exchange chromatography.• Analyzed data with Vector NTI, Spotfire, Excel, Access, and genome browsers.

Studied HIV-1 Rev & Nef and cellular transport proteins.• Molecular biology: cloning, mutagenesis, oligonucleotide design, restriction maps, PCR. • Protein work: expression, purification, ELISA & Western, microinjection, yeast 2-hybrid, IP.• Cell culture: transfections, retroviral packaging, cell fusions, HIV-1 and SIV culture.• Used on-line databases, sequence-analysis and other programs. Co-authored 7 papers.

Laboratory of Pediatric Nephrology• Tissue explanting, culture, and immunoflourescence.

Gradate Student course and lab work in Molecular Genetics, Immunology, Microbiology• Basic molecular biology, cell culture, animal handling.

Taught Earth Science, Physical Science & Biology to middle-school students: course and lab preparation & instruction. Created health program and other curricular changes. Led science program (K-9th grades).

Observed and assisted Doctors in Internal Medicine Clinic; took part in Beta-blocker clinical trial.