Thai Dinh Email and Phone Number
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Highly motivated scientist with 20+ years of experience at big Pharma and Small Biotech in drug discovery of Antibody, Protein, Oligonucleotide and small molecules.Strong expertise in assay development especially in area of label-free technologies for screening, characterization and binding kinetics of therapeutic molecules.Exceptional in problem solving and data analysis. High degree of self-motivation and attention to detail.
Quidel
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- quidel.com
- Employees:
- 880
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Staff ScientistQuidel Jun 2022 - PresentSan Diego County, California, United StatesAntibody discovery in R&D
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ScientistJanssen, Pharmaceutical Companies Of Johnson And Johnson Jul 2003 - Nov 2020Greater San Diego Area1. Lead in assay development and project management for discovery and optimization of therapeutic monoclonal antibodies.2. As in-house expert, evaluate, acquire and implement label-free platforms such as Biacore, ProteOn, Octet and KinExa in characterization of protein interaction.3. Develop and implement high throughput SPR methods for measuring kinetics affinity and epitope binning.4. Develop methods to characterize and analyze Fc functions, PTM (Posttranslational modification) samples of mAb candidates, and bispecific antibody including Duobody platform.5. Develop SPR methods to characterize and determine affinity of membrane protein targets on Lipoparticles and strong mAb binders in single pM affinity.6. Scouting new platforms and technologies for antibody discovery and antibody characterization.7. Develop SPR methods to characterize antibodies with dependent off-rate at lower pH vs. neutral pH. -
ScientistChugai Biopharm. Inc 1996 - 2003Greater San Diego Area1. Develop and implement cell based assays to screen and provide SAR in support of nuclear hormone receptor program.2. Develop mechanistic assay to measure response of kinase inhibitors.3. Develop gene expression assays to quantify mRNAs in response to Vitamin D receptor modulators.4. Implement High Content Screening (Cellomics) for Cell Pharmacology group.5. Identify new technologies to be used in the development of assays for screening and characterizing of small molecules.6. Work with CRO on vivo PK and toxicity study for Malonyl CoA Decarboxylase (MCD) inhibitors.7. Secondary assay development and lead compounds optimization for VEGF(flt) program.8. HTS screening, secondary assay development and characterization of novel MCD inhibitors. Two classes of inhibitor were discovered for cardiovascular research project.9. Evaluate and implement diagnostic assays to measure Glucose and Insulin in plasma samples.
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Senior Research AssociateGen-Probe 1994 - 1996Greater San Diego Area1. Isolation and characterization of peptides mimicking the function of Erythropoietin (EPO), Interleukin-6 (IL-6), and Interleukin-1 (IL-1) by using Phage display technology.2. Identification of VEGF(flt) lead from small molecule library.3. Characterize the binding of small molecules, fusion proteins using BIAcore.4. Base composition analysis of phosphorothioate oligomers by capillary gel electrophoresis.5. Synthesis and modification of DNA and RNA for antisense program.6. Developing 15umol protocol to scale up the synthesis of phosphorothioate oligo on Expedite synthesizer.7. 35S labeling oligodeoxynucleotides via Hydrogen Phosphonate Synthesis.8. Study animal pharmacokinetic and tissue distribution of 35S label oligodeoxynucleotide phosphorothioates.
Thai Dinh Skills
Thai Dinh Education Details
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Cum Laude Diploma
Frequently Asked Questions about Thai Dinh
What company does Thai Dinh work for?
Thai Dinh works for Quidel
What is Thai Dinh's role at the current company?
Thai Dinh's current role is Research Scientist at Janssen, Pharmaceutical Companies of Johnson and Johnson.
What is Thai Dinh's email address?
Thai Dinh's email address is th****@****sen.com
What schools did Thai Dinh attend?
Thai Dinh attended University Of California, San Diego.
What are some of Thai Dinh's interests?
Thai Dinh has interest in Running And Biking 2, Green Buildings And Prefab Homes, Favorite Architect Frank Lloyd Wright, Tom Kundig.
What skills is Thai Dinh known for?
Thai Dinh has skills like Antibody Enginnering And Discovery, Project Management For Antibody Discovery, Culture And Pharmacological Treatment Of Cell Lines, Use Cellomics System For High Content Screening, Molecular Biology Techniques, Pharmaceutical Industry, Biotechnology, Drug Discovery.
Who are Thai Dinh's colleagues?
Thai Dinh's colleagues are Isabelle Santos, Ron Bourland, Rina Harper, Christian Holmes, Howell Manalo, Russell Ivy, Chris Columbus.
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