Thamires Pimenta Email & Phone Number

Hoddesdon, England, United Kingdom

Campinas, São Paulo, Brasil

Designing and developing drug formulations and their manufacturing processes, managing projects and interactions in the manufacturing facility.- Conferred with manufacturing and research team leaders to communicate targets and improve outcomes from the project tasks.- Evaluated and implemented scale-up from pilot to industrial batches, following the batch, launching, and registration activities.- Performed evaluation and investigation of quality and process deviations to achieve the company’s standards.- Produced and submitted registration documents to meet the standards of the Brazilian regulation body (ANVISA).- Design and execute formulation trials, analytical testing and evaluate stability data to finalise formulation composition.- Develop manufacturing processes for R&D formulations to technical transfer.- Product development through QbD, using risk assessment and FMEA.- Write/review master formulas, manufacturing procedures, SOPs, stability protocols/reports, process validation protocols/reports, Product Development Reports.- Follow industrial batches, launch, and post registration activities to improve processes (troubleshooting, inclusion of new dosages, new coatings, inclusion of API manufacturer).- Evaluation and investigation of quality and process deviations.- Performing change control activities and CAPA.- Use of SAP for manufacturing and maintenance activities.- Preparation of tech-transfer documentation, manufacturing and packaging instructions, and in-process control for solid and semi-solid products.- Assessment of analytical results of dissolution profile, impurities, API, and pre-formulation.

Responsible for supervising the pharmaceutical manufacturing team to ensure efficient execution of the manufacturing operations to fulfil the production goals.- Responsible for leading a team (15 production technicians) to attend production schedules of wet granulation (high-shear, fluidized bed, mill), dry granulation (compress roller, mill), compression, automatic capsule filling and coating machines. Also, primary and secondary packaging lines.- Responsibilities included training the production crew, directing work, assisting with performance appraisals.- Conferring with managers, engineering, and other staff regarding manufacturing capabilities, production timeframe to facilitate production process.- Investigation and implementation of initiatives for quality improvement and cost reduction.- Reevaluation of Standard Operating Procedures (SOPs) to ensure consistent compliance.

Rio De Janeiro E Região, Brasil

Assistance in the monitoring of production processes and several continuous improvement projects applying Lean tools.

Rio De Janeiro E Região, Brasil

- Study of times, movements and setup to implement better practices, increasing production efficiency.- Compilation of KPI for tier meeting, investigating possible actions to meet goals.- Investigation of quality and performance deviations.- Assistance in the implementation of HSE (Health, Safety and Environment) initiatives.

Rio De Janeiro E Região, Brasil

Scientific initiation at the Laboratory of Protein Aggregation and Amyloidosis with emphasis on the area of Medical Biochemistry with the objective of finding new functional amyloids for the resolution of diseases caused by the accumulation of proteins in the nervous system. For this, basic laboratory techniques were used, such as: - Purification of protein by HPLC, - Cultivation of bacteria, yeasts, - Electrophoresis, - PCR,- Search and reading of scientific articles to support the research in databases recognized worldwide.

Postgraduate Degree, Desenvolvimento Farmacotécnico E Inovação Aplicado A Industria Farmacêutica

Bachelor Of Pharmacy - Bpharm, Pharmacy And Biochemistry