Thanyashanthi (Thanya) Nitya-Nootan Email & Phone Number

Mississauga, ON, CA

Hamilton, Ontario, Canada

Hamilton, Ontario, Canada

• Lead several projects, development of R&D screening process for identifying new leads, cell model creation and Invitro assay development for Cancer Immunotherapy Research TAC Technology.
• Lead the cell model engineering project successfully: Engineering of cell lines required for new target evaluation (Tumor lines and T cell engineering).
• Lead the cell model creation projects for external collaborators successfully.
• Lead the generation of TAC01-HER2 in vitro pharmacology data in support of the IND submission (example: Cell model creation, in vitro function and Toxicity assays.
• Complete the screening of new binders TAC constructs and generate data packages for external collabrators
• Optimized R&D T cell production and Invitro-cytotoxicity and screening assays.

• Designed, developed, and implemented In-vitro screening assays, leading to characterization of physicochemical, pharmacological, pharmacokinetic, metabolic and toxicological properties of drug candidates in cell-based.
• Collaboration with CRO’s on study projects
• In-vitro experimental designs, implementation and troubleshooting
• Designing and conducting studies to identify the mechanism of action of new molecules
• Execute In-vitro studies to determine toxicity of new molecules.
• Data analysis and Report writing

Toronto, Canada Area

Conduct Non-clinical In-vitro studies for different projects: Cell based Toxicity assays, assays to determine mechanism of action of the molecule and screening assays.SWOT AnalysisData Analysis and Report Writing. Excellent Time Management and Project ManagementSpecialties Cell Culture experience: Human Bone marrow cells, Human Fibroblast, Human.

Ottawa, Canada Area

Completed several non-clinical In-vitro studies (Product characterization).Written SOP for non-clinical departmentDocumentation lead for non-clinical (protocols, SOPs, Equipment SOPs)Cell culture, molecular biology (DNA gels, RNA isolation, Western blots, Immuno-cytochemistry)Purchasing for non-clinical Excellent customer-service, communication and.

Cardiovascular Research:Conducted research for cardiovascular related disease.Expression of beta-Camkinase protein, Protein Isolation, Purification, Western Blots, DNA gels, Restriction Digest, molecular and cellular cloning, Fractionization of rabbit skeletal muscle and etc........