Thierry Schmidlin Email & Phone Number

Mainz, Rhineland-Palatinate, Germany

United Kingdom

Oxford, United Kingdom

Antigen Discovery GroupIndustry-funded position managed by a biotechnology company focusing on antigen discovery and immunotherapy

Stuttgart Area, Germany

• Establishment of a single-platform multi-OMICS workflow for the analysis of human tissue in the clinics• Patient specific characterization of cholestatic liver disease to generate molecular OMICS-networks• Major techniques: untargeted metabolomics, fresh frozen tissue, multi-OMICS

Utrecht Area, Netherlands

Principal Investigator: Dr. Maarten Altelaar and Prof. Albert Heck• Development of a LC-MS based method for a systematic screening of kinase activities based on conserved activation sites (commercialized as QuantaKinome™ by Pepscope - patent pending)• Detection of a potential biomarkers for first line drug resistance in melanoma• Establishment of DIA workflows incorporating EThcD fragmentation, allowing the use of decision-tree-based spectral libraries for targeted data extraction• Collaborations with research groups focusing on neurobiology, antibody research and histone modifications leading to novel assays currently employed in obesity research and epigenetics• Targeted quantification of phosphorylated peptides and neuropeptides by LC-MS including SRM, PRM, data-independent acquisition, MRM cubed• Various steps in workflow automation for phosphopeptide enrichment by a liquid handling platform to facilitate high-throughput applications• Major techniques: phosphoproteomics sample preparation from various sample types, neuropeptide extraction from hypothalamus samples, membrane protein enrichment, nano-LC-MS (DDA, DIA, SRM, PRM)

Basel, Basel-Town, Switzerland

Irregular involvement as research assistant in the lab of Prof. Martin Spiess, Biozentrum of the University of Basel in parallel to my high school education.Main research focus: Elucidation of the topology of mutated yeast Sec61 translocon variantsMajor techniques: site-directed mutagenesis, biotin-maleimide crosslinking, western blot analysis

Doctor Of Philosophy - Phd, Analytical Chemistry

Thesis Title: Novel Methods and Applications of Data-Independent and Targeted Mass Spectrometry; Towards Robust Quantification.

Master Of Science (Msc), Biology

MSc in Biology with a Major in Biological Chemistry Master Thesis, ETH Zurich (2013) Principal Investigator: Prof. Ruedi Aebersold •.

Bachelor Of Science (Bsc), Biology

Matura