Yi Dong Email & Phone Number

Norwood, Ma, Us

Bedford, Ma, Us

- Project technical lead, working with chemistry and engineering teams to deliver two new products.- Design and organize tests according to CLSI guidelines for 510(k) submission.- Manage and develop direct reports.

Billerica, Massachusetts, Us

- Developed a p-Tau217 assay on Simoa HDX platform for a pharmaceutical customer.- Optimized beads-antibody conjugation and various reagent formulation.

Forchheim, De

- Product owner of Assay System Integration team. Focused on delivering analytical performance through proper integration of analyzer, sensors, and reagents.- Continued optimization and design transfer of BUN and pO2 sensors.

Forchheim, De

- Assay development for Creatinine and BUN sensors used in BGEM analyzers.- Product owner of reagent team, working on formulation, stability, and design transfer.- Continued optimization of micro pO2 sensors for blood gas analysis.

Forchheim, De

- Assay development and reagent lyophilization of lipids project (HDL,LDL, Triglycerides).-Sensor development and process optimization of pO2 blood gas sensor based laser microfabrication.

Woburn, Ma, Us

- Responsible for developing consumables used in point-of-care immunoassays for tPSA, testosterone, vitamin-D and so on. Reduced assay background, improved internal-positive control, developed testosterone-release and detection mechanism, conjugated vitamin-D to protein carrier and co-developed vitamin-D release mechanism.- Responsible for developing and testing processes and instruments for various manufacturing steps including liquid dispensing, lyophilization, surface treatment, lamination/bonding, and mechanical assembly. Reduced assay manufacturing process time from 22 hr to 30 minutes. Optimized lyophilization formulation to reduce blood clog, increase protein stability and improve assay consistency.- Contribute to root cause analysis of product failure modes, and map root causes to needed manufacturing process improvements. - Work with Engineering team to develop specifications for manufacturing equipment.- Work closely with QC team to create and maintain quality system. Train manufacturing and QC staff for new process, equipment, and inspections.-

- Responsible for optimizing/enhancing immuno-isolation performance of CTC microfluidic chip.- Optimized soft embossing protocol and provided technical support for plastic chip fabrication team.- Enhanced immuno-isolation rate of CTC by 80%. Reduced background from blood by over 90%. - Optimized blood sample processing protocol and reduced leukocyte adsorption by 50-80%.- Optimized microfluidic chip design together with consultants that lead to 6X chip processing throughput and injection-molding ready design features.

Biopolymer coated microwell arrays for high throughput screening of drug-cell interactions.Hydrogel microarray development for tissue engineering applications.

Riverside, Ca, Us

Developed surface coating on polymer, glass and metal for biosensing applications.Developed fluorescence, SPR and SPR imaging platform for protein interaction analysis and toxin detection in flood water, milk, and human serum.Developed on chip polymerization for SPR signal enhancement.DNA/protein/polymer microarray with SPRi analysis.

Pudong New Area, Shanghai, Cn

Micro and nano lithography and plasm dry etch process development.Developed production process for about 15 commercial products.

上海, 上海市, Cn

Developed silver/ceramic catalyst of selective oxidation reactions.Materials study and surface characterization with FTIR/SERS/XPS/SEM/XRD/DSC/TPD.

Phd, Analytical Chemistry

Master, Physical Chemistry