Thomas Glover Email & Phone Number

Boston, MA, US

Thousand Oaks, CA, US

Tarrytown, New York, US

• Utilized QbD approach to optimize conjugation and purification of novel antibody drug conjugates for quality, scalability, and cost in support of IND-enabling toxicology batches and FiH clinical trials for 4+.
• Conjugated potent small molecules to 7+ antibodies utilizing enzyme and lysine method (site specific, random) for use in bench studies, analytical and formulations development, and preclinical studies to drive program.
• Leveraged analytical skills to execute SEC, RPLC, and fluorescence-based characterizations for preclinical material, reducing analytical burden on external groups by over 20% and enabling feedback control through.
• Designed novel IPC to measure ADC CQAs (DAR, HMW) using SEC, reducing processing time to just 15 minutes.
• Developed novel methods for in process sample prep and LC calibration using root cause analysis and Empower methods, significantly reducing inter-lab variability in analysis (HMW%, LMW%, recovery%) for risk management.
• Improved high-throughput screening of chromatography modalities (HIC, affinity, IEX, MMC) to pinpoint resin leads for QbD purification optimization, leveraging Unicorn automation and controls to reduce benchwork time.

Silver Spring, MD, US

• Demonstrated 15% improvement in sensitivity and robustness of ASTM protocol for evaluating anti-microbial medical devices (wound dressings) by replacing plate-based quantification (CFU/mL) with qRT-PCR.
• Showcased phenotypic changes in bacterial strains in response to antimicrobials, using cell-culture, RNA isolation, centrifugation, extraction, reverse transcription, primer design, qRT-PCR, and statistical analysis.
• Published findings in PlosOne, utilizing technical writing, interdisciplinary collaboration, and literature review skills.
• Implemented revised protocol for evaluation of PPE efficacy against transmission of chemical and biological agents. Utilized western blot and qPCR quantification in conjunction with SEM and DMA characterizations.

Baltimore, Maryland, US

• Led students in leveraging Aspen and SIMULINK to optimize industrial chemical processes for > 99% yield and purity.
• Showcased lean manufacturing approach to optimize operating conditions for yield and >20% cost reductions through unit operation elimination, recycle, raw material choice, catalyst choice, and reactor and column.
• Mentored students on 10x process-scaleup including validation, geometric and dynamic similarity calculations, and cost.

Baltimore, Maryland, US

• Drove student development of R&D timelines for commercialization of over 8 chemical engineering products, with emphasis on scaleup of product manufacturing, commercialization, regulatory compliance, and profitability.
• Focused on cost estimation to decide on long-term projects with highest return, with emphasis on DCF analysis, market research, differentiability, brand equity, competitive advantage, and senior management communication.

Baltimore, Maryland, US

• Graded business case studies incorporating modern business topics, driving more positive student feedback.
• Selected business cases to emphasize unique issues in management, quality control, customer service, and marketing, increasing course relevance and student engagement.

• Assessed impact of glucose metabolism under anaerobic stress conditions on CHO cell growth, viability, and titer.
• Conceptualized cyanobacteria-algae co-culture system for cost effective biofuel production, utilizing genetically introduced sucrose and glutamate transporters for nutrient exchange, obviating need for feedstock.

Baltimore, Maryland, US

• Led a team of 5 writers to drive audience growth for student startup incubator, increasing article views 50x.
• Interviewed student and Baltimore-based founders to understand their mission, struggles, and help market their business. Drove increased website engagement by leveraging social media channels and in-article.

• Compiled equity research reports for use by traders in execution of high frequency, latency sensitive trades.
• Refined scope and analysis of research products based off feedback from traders for better knowledge transfer.

Master Of Engineering - Meng, Chemical And Biomolecular Engineering

Bachelor'S Degree, Chemical And Biomolecular Engineering, Entrepreneurship & Management Minor

Education record