Thomas Glover work email
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Results oriented Process Development Scientist with 4+ years experience in benchwork, process and analytical development, and technical communications. Proven track record in risk assessment, technical writing, and cross-functional collaborations.
Regeneron
View- Website:
- regeneron.com
- Employees:
- 16494
- Company phone:
- + 0120-790-549
-
Process Development EngineerRegeneronBoston, Ma, Us -
Associate Scientist Process DevelopmentAmgen Jun 2024 - PresentThousand Oaks, Ca, Us -
Process Development EngineerRegeneron Aug 2022 - Feb 2024Tarrytown, New York, Us• Utilized QbD approach to optimize conjugation and purification of novel antibody drug conjugates for quality, scalability, and cost in support of IND-enabling toxicology batches and FiH clinical trials for 4+ preclinical programs.• Conjugated potent small molecules to 7+ antibodies utilizing enzyme and lysine method (site specific, random) for use in bench studies, analytical and formulations development, and preclinical studies to drive program decisions. • Leveraged analytical skills to execute SEC, RPLC, and fluorescence-based characterizations for preclinical material, reducing analytical burden on external groups by over 20% and enabling feedback control through real-time analysis. • Designed novel IPC to measure ADC CQAs (DAR, HMW) using SEC, reducing processing time to just 15 minutes.• Developed novel methods for in process sample prep and LC calibration using root cause analysis and Empower methods, significantly reducing inter-lab variability in analysis (HMW%, LMW%, recovery%) for risk management. • Improved high-throughput screening of chromatography modalities (HIC, affinity, IEX, MMC) to pinpoint resin leads for QbD purification optimization, leveraging Unicorn automation and controls to reduce benchwork time. • Developed 5+ SOPs to ensure EHS compliance via comprehensive hazards identification, materials compatibility, Safebridge, HAZOP, and waste management strategies, reducing lab near miss incidents by 50%. -
Orise FellowFda Aug 2020 - Jun 2022Silver Spring, Md, Us• Demonstrated 15% improvement in sensitivity and robustness of ASTM protocol for evaluating anti-microbial medical devices (wound dressings) by replacing plate-based quantification (CFU/mL) with qRT-PCR. • Showcased phenotypic changes in bacterial strains in response to antimicrobials, using cell-culture, RNA isolation, centrifugation, extraction, reverse transcription, primer design, qRT-PCR, and statistical analysis.• Published findings in PlosOne, utilizing technical writing, interdisciplinary collaboration, and literature review skills. • Implemented revised protocol for evaluation of PPE efficacy against transmission of chemical and biological agents. Utilized western blot and qPCR quantification in conjunction with SEM and DMA characterizations. -
Teaching Assistant - Chemical Process DesignJohns Hopkins Whiting School Of Engineering Jan 2022 - May 2022Baltimore, Maryland, Us• Led students in leveraging Aspen and SIMULINK to optimize industrial chemical processes for > 99% yield and purity. • Showcased lean manufacturing approach to optimize operating conditions for yield and >20% cost reductions through unit operation elimination, recycle, raw material choice, catalyst choice, and reactor and column material choice. • Mentored students on 10x process-scaleup including validation, geometric and dynamic similarity calculations, and cost. -
Course Assistant - Chemical Product DesignJohns Hopkins Whiting School Of Engineering Aug 2020 - Dec 2020Baltimore, Maryland, Us• Drove student development of R&D timelines for commercialization of over 8 chemical engineering products, with emphasis on scaleup of product manufacturing, commercialization, regulatory compliance, and profitability analysis.• Focused on cost estimation to decide on long-term projects with highest return, with emphasis on DCF analysis, market research, differentiability, brand equity, competitive advantage, and senior management communication. -
Course Assistant - Principles Of ManagementJohns Hopkins Whiting School Of Engineering May 2019 - Jan 2020Baltimore, Maryland, Us• Graded business case studies incorporating modern business topics, driving more positive student feedback.• Selected business cases to emphasize unique issues in management, quality control, customer service, and marketing, increasing course relevance and student engagement. -
Undergraduate Research AssistantDr. Betenbaugh’S Lab Jul 2019 - Sep 2019• Assessed impact of glucose metabolism under anaerobic stress conditions on CHO cell growth, viability, and titer. • Conceptualized cyanobacteria-algae co-culture system for cost effective biofuel production, utilizing genetically introduced sucrose and glutamate transporters for nutrient exchange, obviating need for feedstock.
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Blog Team DirectorTco Labs Oct 2017 - Feb 2019Baltimore, Maryland, Us• Led a team of 5 writers to drive audience growth for student startup incubator, increasing article views 50x. • Interviewed student and Baltimore-based founders to understand their mission, struggles, and help market their business. Drove increased website engagement by leveraging social media channels and in-article advertisements. . -
Market Research InternVigilant - A Drw Company Jun 2018 - Aug 2018• Compiled equity research reports for use by traders in execution of high frequency, latency sensitive trades.• Refined scope and analysis of research products based off feedback from traders for better knowledge transfer.
Thomas Glover Education Details
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The Johns Hopkins UniversityChemical And Biomolecular Engineering -
The Johns Hopkins UniversityEntrepreneurship & Management Minor -
Greenwich High School
Frequently Asked Questions about Thomas Glover
What company does Thomas Glover work for?
Thomas Glover works for Regeneron
What is Thomas Glover's role at the current company?
Thomas Glover's current role is Process Development Engineer.
What is Thomas Glover's email address?
Thomas Glover's email address is th****@****fda.gov
What schools did Thomas Glover attend?
Thomas Glover attended The Johns Hopkins University, The Johns Hopkins University, Greenwich High School.
Who are Thomas Glover's colleagues?
Thomas Glover's colleagues are Bryan Grygus, John Harris, Michael Mullowney, Amanda Lopez, Cayden Squires, Mia Romijn, Lily Caza.
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