Thomas Korff Email & Phone Number

Cardiovascular research belongs to the most rapidly growing biomedical disciplines as it deals predominantly with diseases that are the leading cause of death in industrial countries. These include, but are not limited to coronary heart disease, cardiomyopathy, hypertension and arterial disease, heart hypertrophy, heart failure, arteriosclerosis, stroke, peripheral arterial disease and varicosis.Our research group investigates responses of endothelial and vascular smooth muscle cells (ECs and VSMCs) to potentially harmful environmental conditions as may be caused by biomechanical, hypoxic or metabolic stress. Such stimuli evoke adaptive mechanisms to maintain cellular functions, which may, however, in the long run also contribute to detrimental remodeling processes of the vessel wall including its inflammation, stiffening, fibrosis and occlusion. In this context, we currently investigate 1) the regulation of EC and VSMC functions in the hypoxic lung and 2) mechanisms of VSMC foam cell formation in arteriosclerotic lesions.Email: korff@physiologie.uni-heidelberg.deWebsite: https://www.medizinische-fakultaet-hd.uni-heidelberg.de/einrichtungen/institute/forschung/herz-kreislauf-physiologie/thomas-korff

Listed skills include Microsoft Office, Microsoft Excel, Microsoft Word, Research, and 2 others.