The lab identified and continues to explore the different inflammatory responses to infection and cigarette smoke in the lungs of neonatal and adult ice. Understanding the unique response of the two groups will provide insight into the differential injury, recovery, and survival between the young and old mice and serve as a targetable pathway for drug development.• Served as laboratory manager• Planned, performed, and interpreted all major experiments• Mastered… Show more The lab identified and continues to explore the different inflammatory responses to infection and cigarette smoke in the lungs of neonatal and adult ice. Understanding the unique response of the two groups will provide insight into the differential injury, recovery, and survival between the young and old mice and serve as a targetable pathway for drug development.• Served as laboratory manager• Planned, performed, and interpreted all major experiments• Mastered micromanipulations of neonatal mice including bronchoalveolar lavage micro-injections and micro-dissection• Designed all schematics and data presentation using Adobe Photoshop and Adobe Illustrator Show less

The lab focuses on the treatment of cystic fibrosis with novel antimicrobial agents. I designed, performed, and interpreted experiments to demonstrate the utility of a synthetic cationic antimicrobial peptide for the treatment of cystic fibrosis and coordinated with the clinical group to obtain feasibility data with human samples.• Highly experienced with biochemical assays, protein analysis, and Western blotting• RNA isolation and analysis

The lab tested the location and extent of microparticle distribution produced by a nebulizer or nasal sprayer to optimize the administration of intranasal drugs. Using a similar technique, the lab seeks to understand mucous clearing from the lungs of cystic fibrosis patients.• Designed and coded a program in C to analyze the data• Helped establish a method for proper nebulizer and nasal spray technique

The lab focused on retinal degenerations, choroidal neovascularization, and proliferative retinopathies. By understanding the role of growth factors and trophic factors in the retina the lab can devise methods to treat diseases such as age-related macular degeneration and diabetic retinopathy.• Retinal mounts – Microdissected the ten-cell-thick retina from neonatal mice for immunohistochemistry• Angiography – Microinjected fluorescein dye to visualize intraocular… Show more The lab focused on retinal degenerations, choroidal neovascularization, and proliferative retinopathies. By understanding the role of growth factors and trophic factors in the retina the lab can devise methods to treat diseases such as age-related macular degeneration and diabetic retinopathy.• Retinal mounts – Microdissected the ten-cell-thick retina from neonatal mice for immunohistochemistry• Angiography – Microinjected fluorescein dye to visualize intraocular arteries• Ultramicrotomy – Only person in laboratory to be able to embed and cut 0.5 micron thick sections of retinas for enhanced cellular resolution Show less