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Thomas Mcnabb is a Senior Analytical Chemist at Cambrex.
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Principal Analytical ScientistCody Laboratories, Inc. Nov 2016 - Jun 2019Cody, WyDeveloped and validated analytical methods for controlled substance APIs under cGMP. Developed & validated ten analytical methods and provided in-process support for API Levomethadone HCl and Methadone HCl projects, using UPLC, chiral HPLC and GC techniques. Inventor for patent application for Methadone HCl process. In-process analytical support for multiple projects. Effectively interacted with engineers, organic chemists, QC, QA and management. Developed HILIC/MS method to separate & detect EME HCl from degradation products and isomers. Identified and assessed compound stability during manufacturing process. Effective and timely trouble-shooting of UPLC, HPLC and GC methods. -
Principal Scientist/ Associate DirectorBayer Consumer Care Oct 2014 - Sep 20163030 Jackson Ave., Memphis, Tn 38151Supported new product development and stability investigations of finished products. Identification of Dextromethorphan impurity in stability study investigation by HRMS.Identified Pseudoephrine-citrate ester complexes in stressed samples by Q-TOF HRMS. Collaborated with analytical team at different sites. Gold Award, 2016. Monitored and identified unknown peaks in stressed samples for Phenylephrine HCl liquid formulations. Resolved Pseudoephrine-sucrose adducts from complex matrix with the use of mass profiler software and confirmed structures with molecular structure correlator software.
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Principal ScientistMerck Consumer Care Jun 2011 - Sep 2014Memphis, TnAnalytical lead responsible for developing, validating and transferring analytical methods for finished products and APIs. Developed & validated HPLC methods for Miconazole Nitrate in Lotrimin. Used cation-exchange SPE to recover active and related compounds from a complex matrix. Compared formulations of Claritin manufactured at different sites and under different regulatory guidance. Wrote dissolution protocols and reports to assess comparability of tablets. Developed and validated new chiral HPLC method to resolve multiple stereoisomers of Clemastine fumarate and achiral related compounds by a single method.
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Associate Principal ScientistSchering-Plough Healthcare Products, Inc. Oct 2001 - Jun 2011Memphis, TnDeveloped test methods to characterize PEG 3350 for MiraLAX Liquid Concentrate by size exclusion chromatography, molecular weight and residual glycols. Achievement Award, 2010. Analytical lead for Claritin Chewable Tablet project to support new NDA filing. Developed & validated of assay, dissolution & related compound test methods. Used QbD to optimize HPLC conditions. Wrote validation protocols & reports, investigation reports and peer review of data. Supervised direct reports and mentored staff members in analytical group. -
Senior Scientist IiGeltek Pharmaceuticals (Genzyme Corp.) Aug 1997 - Sep 2001Waltham, MaSenior Scientist II, Waltham, MA: Analytical lead for anti-obesity project, developed new HPLC/ ELSD methods to quantify lipid classes and detect degradation products in drug candidates.
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Thomas Mcnabb Education Details
Frequently Asked Questions about Thomas Mcnabb
What is Thomas Mcnabb's role at the current company?
Thomas Mcnabb's current role is Senior Analytical Chemist at Cambrex.
What is Thomas Mcnabb's email address?
Thomas Mcnabb's email address is th****@****rex.com
What schools did Thomas Mcnabb attend?
Thomas Mcnabb attended University Of Rhode Island, Northeastern University, Mercer University.
What skills is Thomas Mcnabb known for?
Thomas Mcnabb has skills like Hplc, Analytical Chemistry, Lc Ms, Validation, Glp, Chromatography, Gc Ms, Analytical Methods Development, Stuctural Elucidation, Uv/vis, Mass Spectrometry, Elsd.
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Thomas McNabb
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Thomas McNabb
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