Thomas Van Aelst Email & Phone Number

Wetteren, Be

Wetteren, Flemish Region, Belgium

Head of process chemistry R&D team consisting of 2 Research Chemists (PhD) and 3 lab chemists (BS)

Wetteren, Belgium

- Process chemistry R&D of small molecule APIs and intermediates for the pharmaceutical industry (hands-on route screening, route development, literature search, parameter screening, DoE’s …)- Project management and coordination of 1-2 lab chemists- Writing development reports, lab reports, critical parameter reports…- Tech transfer to Pilot plant and Production for kg to ton scale up- Production support (troubleshooting, root cause analysis, use testing...)

Wetteren, Belgium

- Project lead for scale up of R&D processes in the Pilot plant (100-1000L vessels) in a full GMP environment - Coordination of a team consisting out of 2 process operators and 2 shift supervisors - Determining reactor setup and overseeing production- Writing of master batch records, status updates and campaign reports- Revision of executed batch records, writing deviation reports in cooperation with the QA department- Training of shift supervisors and operators for various processes

Hamme, Flemish Region, Belgium

Basel, Switzerland

- Medicinal chemistry project in the lab of dr. Luca Gobbi aimed at the discovery of a novel PET radiotracer for in house use- Multistep route screening and route optimization - Purification by column chromatography and crystallization- Characterization of end products (1H NMR, MS, LC-MS)- Weekly progress meetings, attended Roche summer school for organic chemistry and presented one poster presentation at the pRED intern symposium

Wetteren, Belgium

- Internship in process chemistry R&D aimed at the development of a synthesis route for the production of an intermediate of an anti-diabetic API. Optimized process running on multi ton scale since 2014- Route screening, route development, literature search and reporting- Analysis by HPLC, LC-MS, 1H NMR and TLC chromatography

Master Of Science (M.Sc.), Chemistry, Cum Laude

Master’s dissertation: “Further development of a solid phase strategy for the synthesis of structurally diverse.

Bachelor Of Science (B.Sc.), Chemistry, Cum Laude

Activities and Societies: Discipuli Pouckii, AstoriaPresident at Discipuli Pouckii (2008-2009), association for Biology and Chemistry.

General Secondary Education, Science And Mathematics (8H)