Thomas Rupp Email and Phone Number
Thomas Rupp work email
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Thomas Rupp personal email
Subject Matter Expert on Oligonucleotide Manufacturing and Analytics.I offer >35 years of technical expertise and hands-on experience on oligonucleotide manufacturing, quality control and downstream purification and isolation; facility design & setup (non-GMP small scale + GMP large scale); dealing with CMO; CMC control strategy development, and much more...In detail:Manufacturing (Synthesis, Analytics, Downstream) of DNA, RNA, 2'-o-Modifiers, Aptamers, Antisense 1st, 2nd, 3rd xth generation, Gapmers, long and complex oligonucleotides, siRNA, miRNA, mRNA, Ribozymes, Immune-stimulatory oligos (CpG), Transcription Factor Decay (TFD), you name it;Development and project management for oligonucleotide-based therapeutics;Process Development, Process Design, Process Optimisation, Scale-Up from bench to multi kilogram scale, Troubleshooting, Technology Transfer, DoE, CMO selection, CMO & proposal discussions, Supervision of Manufacturing campaigns and Batch Record reading;Customised and tailored programming of GE Healthcare Unicorn control software for oligonucleotide synthesis instrumentation (AKTA oligopilot 10/100, OP400, Oligo Process, Asahi Kasei Technikrom synthesiser), purification, analytical and desalting systems;Instrumentation Selection, Facility Design for Oligonucleotide Manufacturing at any scale, Facility Audits, CMO Audits, Instrument and Process Validation and Qualification (IQ/OQ, PQ, DQ);Theoretical and practical workshops on all above mentioned fields;
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Managing DirectorAxolabs Berlin Gmbh Nov 2021 - PresentTechnical Managing Director for planning and commissioning of the new LGC/Axolabs site in Berlin
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Member Of The Oboa (Oligo Board Of Advisors)Asahi Kasei Bioprocess America, Inc. Jul 2021 - PresentGlenview, Il, Us
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BossThomas Rupp Consulting May 2013 - PresentI am finally using my >28 years of experience withing the world of synthetic DNA and RNA to become a freelance consultant for any oligonucleotide-related technical questions, let it be Process Development, Process Streamlining and Optimisation for future Upscale, Process Troubleshooting, Unicorn (GE Healthcare) Programming and Workshops, Facility Design, Synthesis, Purification, Analytics.Questions? Please send me an email!
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Member Of The SabLink Technologies Ltd (Scotland) Jan 2015 - Present
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Member Of The External Advisory BoardDna-Trap Jul 2014 - Oct 2015The DNA-TRAP project is designed to facilitate the exchange of knowledge and technology between 2 leading European research organisations and 2 SMEs (Small and Medium Enterprises) each with an interest in researching the fundamental properties of nanostructured drug delivery systems.For more info see: http://dnatrap-iapp.eu/overview/
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Technical Advisor Oligonucleotide ManufacturingGirindus Ag, Member Of The Solvay Group Apr 2010 - May 2013Initially started as Technical Business Development Manager Europe, then additionally took responsibility in Technical & Application Consulting for our Production Team in Cincinnati to better utilize my long-yeared experience and knowledge in the oligonucleotide field.Main focus was training of Operators on nucleic acid chemistry and instrumentation for oligonucletide manufacturing as well as process development and optimisation, internal audits and trouble shooting.
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Bioprocess Customer Application Support SpecialistGe Healthcare Apr 2002 - Mar 2010Chicago, UsResponsible for all oligonucleotide-related business of GE Healthcare from small scale academic to process scale industry within Europe and Asia.Customer trainings (theoretical / practical) on DNA/RNA synthesis and downstream processes.One day theoretical workshops at international conferences (Tides, Eurotides and Asiatides).Process development, Process optimisation, Process troubleshooting.Certified for IQ/OQ and Validation of instrumentationAny oligo-related specialities (facility-design, process development, specialized Unicorn programming on AKTA synthesisers (implementation of PNA, RNA, LNA, Gapmers, Aptamers, etc.)Knowledge base for GE Healthcare Sales force and Marketing for oligonucleotide business -
ScientistNoxxon Pharma Ag 1998 - 2002Design and setup of the oligonucleotide synthesis, downstream and analytical lab. Development of synthesis and purification processes for long (up to 100 mer) RNA and long (up to 120mer) DNA aptamers.Setup of robotics for aptamer selection.
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Head Of ManufacturingInnovir Laboratories - Ribonetics Gmbh Mar 1995 - Sep 1998Design and setup of a synthesis lab for synthetic Ribozymes.Process development, Process optimization around Ribozyme manufacturing.Development of automation processes for target molecule identification.Network Administration.
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Head Of Technical StaffLoyola University Medical Center Jan 1994 - Mar 1995UsSetup of molecular biology laboratories for HPV (human papilloma virus) research in the research group of Prof. Lutz Gissmann.Training of lab personnel in general molecularbiology methods and basic virologySetup of a DNA/RNA synthesis core facility. -
CtaEmbl Jan 1991 - Dec 1993Heidelberg, DeDevelopment and commercial launch of a 10 / 96 column DNA synthesiserCo‐Development of a fluorescent DNAsequencer (ALF) and methods for sequencing.Member of the international sequencing project "Saccharomyces Cerevisae"Development of a new large scale RNA synthesis process on the ABI 390Z synthesiser (project with ABI, Inc.) -
CtaDkfz Jul 1983 - Dec 1990Heidelberg, DeDesign, setup and running of the DKFZ‐internal Core Facility for both, synthesis of oligonucleotides and sequencing.Development and commercial launch of a proprietary PCR‐machine.Introduction to molecular biology (esp. virus research on HPV 16) in the research group of nobel laureate Prof. Harald zur Hausen.
Thomas Rupp Skills
Frequently Asked Questions about Thomas Rupp
What company does Thomas Rupp work for?
Thomas Rupp works for Asahi Kasei Bioprocess America, Inc.
What is Thomas Rupp's role at the current company?
Thomas Rupp's current role is Think positive! There is a problem to every solution!.
What is Thomas Rupp's email address?
Thomas Rupp's email address is tr****@****dus.com
What are some of Thomas Rupp's interests?
Thomas Rupp has interest in Therapeutic Oligonucleotides, Spiegelmers, Conjugation, Cgmp, Gmp, Health, Oligonucleotides, Synthetic Rna, Sirna, Troubleshooting.
What skills is Thomas Rupp known for?
Thomas Rupp has skills like Biowissenschaften, Biotechnologie, Dna, Technologietransfer, Hplc, Manufacturing, Sirna, Rna, Gmp, Oligonucleotide Synthesis, Purification, Chromatography.
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