Thomas Rupp Email & Phone Number

Technical Managing Director for planning and commissioning of the new LGC/Axolabs site in Berlin

Glenview, Il, Us

I am finally using my >28 years of experience withing the world of synthetic DNA and RNA to become a freelance consultant for any oligonucleotide-related technical questions, let it be Process Development, Process Streamlining and Optimisation for future Upscale, Process Troubleshooting, Unicorn (GE Healthcare) Programming and Workshops, Facility Design, Synthesis, Purification, Analytics.Questions? Please send me an email!

The DNA-TRAP project is designed to facilitate the exchange of knowledge and technology between 2 leading European research organisations and 2 SMEs (Small and Medium Enterprises) each with an interest in researching the fundamental properties of nanostructured drug delivery systems.For more info see: http://dnatrap-iapp.eu/overview/

Initially started as Technical Business Development Manager Europe, then additionally took responsibility in Technical & Application Consulting for our Production Team in Cincinnati to better utilize my long-yeared experience and knowledge in the oligonucleotide field.Main focus was training of Operators on nucleic acid chemistry and instrumentation for oligonucletide manufacturing as well as process development and optimisation, internal audits and trouble shooting.

Chicago, Us

Responsible for all oligonucleotide-related business of GE Healthcare from small scale academic to process scale industry within Europe and Asia.Customer trainings (theoretical / practical) on DNA/RNA synthesis and downstream processes.One day theoretical workshops at international conferences (Tides, Eurotides and Asiatides).Process development, Process optimisation, Process troubleshooting.Certified for IQ/OQ and Validation of instrumentationAny oligo-related specialities (facility-design, process development, specialized Unicorn programming on AKTA synthesisers (implementation of PNA, RNA, LNA, Gapmers, Aptamers, etc.)Knowledge base for GE Healthcare Sales force and Marketing for oligonucleotide business

Design and setup of the oligonucleotide synthesis, downstream and analytical lab. Development of synthesis and purification processes for long (up to 100 mer) RNA and long (up to 120mer) DNA aptamers.Setup of robotics for aptamer selection.

Design and setup of a synthesis lab for synthetic Ribozymes.Process development, Process optimization around Ribozyme manufacturing.Development of automation processes for target molecule identification.Network Administration.

Us

Setup of molecular biology laboratories for HPV (human papilloma virus) research in the research group of Prof. Lutz Gissmann.Training of lab personnel in general molecularbiology methods and basic virologySetup of a DNA/RNA synthesis core facility.

Heidelberg, De

Development and commercial launch of a 10 / 96 column DNA synthesiserCo‐Development of a fluorescent DNAsequencer (ALF) and methods for sequencing.Member of the international sequencing project "Saccharomyces Cerevisae"Development of a new large scale RNA synthesis process on the ABI 390Z synthesiser (project with ABI, Inc.)

Heidelberg, De

Design, setup and running of the DKFZ‐internal Core Facility for both, synthesis of oligonucleotides and sequencing.Development and commercial launch of a proprietary PCR‐machine.Introduction to molecular biology (esp. virus research on HPV 16) in the research group of nobel laureate Prof. Harald zur Hausen.