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Based on extensive experience gained through over 25 years of oversight and championing of broad pipelines of diverse drugs, I am well-versed in common scientific, non-clinical, translational, clinical, business, and regulatory issues common to drug development and approaches to avoid or solve these issues. Underpinning this experience is a solid scientific background in oncology, immunology, and gene therapy with first or senior author publications in Science, Cell, Nature Medicine and Nature Biotechnology and primary inventorship on over 30 issued patents. I have significant experience in managing groups of scientists providing preclinical in vivo pharmacology and translational research to drive multiple oncology, immunotherapy, autoimmune, and angiogenic projects in Discovery and Early Development and have provided leadership to drive the design of first in man and proof of concept studies through close, cross-functional interaction on integrated project teams. In addition, I have led numerous strategic efforts to enhance drug development including the creation of biomarker discovery and combination therapy strategies for oncology and the development of workflows and criteria for drug discovery and early development. Specialties: Cell therapy, oncology, immunology, translational medicine, drug discovery and development, gene therapy
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Chief Scientific OfficerGentibio Sep 2020 - PresentCambridge, Massachusetts, Us -
Senior Vice President DiscoveryRubius Therapeutics Mar 2019 - Sep 2020Cambridge, Massachusetts, Us -
Vice President Research And DevelopmentRubius Therapeutics Oct 2016 - Mar 2019Cambridge, Massachusetts, Us
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Vice President, Research & DevelopmentMerrimack Pharmaceuticals Jan 2011 - Oct 2016Cambridge, Massachusetts, Us -
Sr. Director, ResearchMerrimack Pharmaceuticals Feb 2009 - Feb 2011Cambridge, Massachusetts, Us
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Sr. Director, Exploratory PharmacologyEmd Serono Feb 2004 - Nov 2008Boston, Massachusetts, UsLead a team providing scientific and pharmacological support for multiple oncology projects in Discovery or Early Development, including in vivo target validation, MoA determination, evaluation of combination therapy potential, and biomarker discovery. Ensure integration with Discovery and global clinical and non-clinical lines during early phase development. -
Sr. Director, Preclinical SciencesGenvec Nov 1993 - Feb 2004Gaithersburg, Md, UsLed a group of scientists who created a patented, cutting-edge technology platform that enables the targeting of therapeutic genes to sites of disease. Led efforts to patent the targeting technology with at least 19 issued U.S. patents. Established scientific leader in the field with over 60 articles in top-ranked journals including lead or senior author on publications in Science, Cell, Nature Medicine, and Nature Biotechnology. Played key roles in the preclinical and clinical development of GenVec’s drugs for cancer and heart disease.
Thomas Wickham Skills
Thomas Wickham Education Details
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Cornell UniversityBiochemical Engineering -
Carnegie Mellon UniversityChemical/Biochemical Engineering
Frequently Asked Questions about Thomas Wickham
What company does Thomas Wickham work for?
Thomas Wickham works for Gentibio
What is Thomas Wickham's role at the current company?
Thomas Wickham's current role is Chief Scientific Officer at GentiBio.
What is Thomas Wickham's email address?
Thomas Wickham's email address is th****@****stx.com
What is Thomas Wickham's direct phone number?
Thomas Wickham's direct phone number is (617) 679*****
What schools did Thomas Wickham attend?
Thomas Wickham attended Cornell University, Carnegie Mellon University.
What skills is Thomas Wickham known for?
Thomas Wickham has skills like Biopharmaceuticals, Drug Development, Life Sciences, Drug Discovery, Clinical Development, Oncology, Pharmaceutical Industry, Biomarkers, Cancer, Immunology, Cell Biology, Cell.
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