Instructor of the following courses: General, Organic and Biochemistry Organic Chemistry General Chemistry Laboratory

General chemistry laboratory instructor.

 Research focused on pre-clinical evaluation of combination therapies for melanoma Elucidation of epigenetic regulation of DNA repair pathways using western blotting Performed toxicity and survival assays in vitro

* Syntheses of small molecule inhibitors of Chk2, a DNA damage cell cycle checkpoint -Improved synthesis of small heterocycles with indole core -Characterization using Varian based NMR techniques, UV, IR, mass spectroscopy (LC-MS), chromatographic methods (flash, thin layer, gravity)* In vitro evaluation of Chk2 inhibitors -Microbiology, cell biology, maintaining mammalian cell cultures -Toxicity evaluation using viability assays -Cell cycle analysis (FACS) using propidium iodide, BrdU, FITC -Western blot analysis -Cloning survival analysis -Radiolabeled kinase profiling -Luciferase gene transcription assays

Investigation of DNA adducts formed from peroxidase-activated phenolsSynthetic approach for evaluating phenol-induced DNA damage

* Sample preparation and analysis of polycyclic aromatic hydrocarbons in human urine using mass spectrometry and HPLC* Development of phenanthrene tetraol assay to measure carcinogens in human blood