Consulting and advisory services for drug discovery, providing expertise and services in the following areas:• Organic, bioorganic, and medicinal chemistry and chemical biology• Hit identification through biological and virtual screening• Hit to lead optimization• Patent review and analysis• Scientific and medical writing• Scientific advisory boards• Due diligence

Head of chemistry and member of leadership team at seed-stage biotech/pharma startup company.• Designed chemistry to create a new class of oligomeric DNA-targeting medicines, including antibody-oligonucleotide conjugates (AOCs).• Created fit-for-purpose conjugates of oligonucleotides, peptide nucleic acids (PNAs), and pyrrole-imidazole polyamides (PIPs).• Planned and tested design-build-test cycles to generate therapeutic leads, including the use of AI/ML-based prediction tools.• Developed strategic plan for growth of the platform from discovery to delivery of clinical candidates.• Managed network of international CROs and local scientific team.• Identified and developed a network of advisors and key opinion leaders (KOLs).• Worked with patent attorney on developing IP strategy.• Clearly communicated complex concepts within the company, to the CEO, and to investors.

Led and managed platform chemistry for series A-funded biotech/pharma startup company.• Designed and synthesized bespoke chemical library for covalent drug discovery.• Developed library screening strategies.• Evaluated high throughput chemoproteomics data to identify hits.• Elaborated a weak screening hit into a compound series for a therapeutic program.• Computer-aided design and molecular modeling.• Managed international CROs.

• Led an interdisciplinary and multinational team of scientists in chemical biology and medicinal chemistry to invent tools to enable innovative experimental approaches to biological questions:(1) Design and synthesis of small molecules for light-mediated activation of biological effectors to study neurobiology, embryonic development, olfaction, and other complex physiology.(2) Target-based discovery and screening of inhibitors of CaaX protease Ras converting enzyme (Rce1) to probe the role it plays in regulating the function of the oncogene Ras.(3) Structure-based discovery and design of potential drug leads for malaria, cancer, andcoronaviruses.(4) Biological evaluation of C-glycoside-based inhibitors of sodium-glucose co-transporters SGLT1 and SGLT2 as leads for diabetes drugs.(5) Collaborated with engineer to develop magnetoencephalography (MEG) as a probe of cell physiology and cancer screening tool.• Collaborated internationally with neurobiologists, cell biologists, biochemists, developmental biologists, computational chemists, and experimental physical chemists.• Helped build core research instrumentation facilities.• Recruited, hired, mentored, and evaluated research staff and faculty members.• Partnered with NY colleagues to create joint NYU/NYUAD PhD program in chemistry.• Communicated science to student, lay, and professional audiences.• Engaged in active program of research, teaching, and service.

• Revised chemistry BS degree curriculum to meet accreditation standards.• Designed undergraduate capstone research program for chemistry students.• Recruited new faculty members.• Managed faculty teaching activities, student recruitment, and seminar program.

• Led an innovative and successful research program in bioorganic chemistry and chemical biology to develop small organic molecules as probes of cell physiology.• Oversaw budgets of major grant awards from government and philanthropic funding agencies.• Managed research staff of postdoctoral associates, graduate and undergraduate students.• Taught courses in chemistry at the undergraduate and graduate level.• Communicated science to student, lay, and professional audiences.• Engaged in active program of research, teaching, and service.

• Created innovative and successful research program in bioorganic chemistry and chemical biology to develop small organic molecules as probes of cell physiology.• Oversaw budgets of major grant awards from government and philanthropic funding agencies.• Managed research staff of postdoctoral associates, graduate and undergraduate students.• Taught courses in chemistry at the undergraduate and graduate level.• Communicated science to student, lay, and professional audiences.• Engaged in active program of research, teaching, and service.

Institute of Advanced EnergyHost: Takashi Morii• Worked on RNA-based technology for biological sensing.

Doctoral Student Education & Career Preparation ProjectPrincipal Investigator: Chris M. Golde• Investigated the career goals and career preparation of doctoral students.• Explored the process of doctoral education from the students’ perspective.• Co-authored "At Cross Purposes: What the experiences of doctoral students reveal about doctoral education"

Research Advisor: Roger Y. Tsien• Studied 2-photon excitation as a means to regulate the action of biological effectors.• Explored the synthesis of fluorescent and luminescent probes of cell physiology.• Evaluated properties of a redox sensitive GFP in mammalian cell culture.

Synthesized structural analogs of drug leads.Supervisor: George Chang

Synthesized intermediates of experimental drugs.Supervisor: Marc Caddell

Measured the pKa of experimental drugs and drug candidates.Supervisor: Chris Lipinski