Predicting tissue of origin (TOO) for cancer of unknown primary (CUP) cases from OmniSeq assay using Explainable Machine Learning methods.

• Developed BIG-DE (https://tarunmamidi.shinyapps.io/lsuhsc_big_de/), a Shiny-based application for exploring, visualizing, and analyzing gene expression data with minimal coding required.• Mapping the genetic and epigenetic mutation landscape in indolent and aggressive prostate cancer.

• Analyzed spectral data of proteins using Trans Proteomic pipeline. • Part of developing a tool, TopPIC which retrieves PTM’s and Modifications of protein sequences. • Constructed and developed a database called GTRAP providing information from gene level to protein level. (https://g-trap.000webhostapp.com/)• Constructed golden standard text mining repertoire on drug-drug interactions from pubmed articles.• Worked in collaboration with Dr. Mathew Palakal on sub-classifying… Show more • Analyzed spectral data of proteins using Trans Proteomic pipeline. • Part of developing a tool, TopPIC which retrieves PTM’s and Modifications of protein sequences. • Constructed and developed a database called GTRAP providing information from gene level to protein level. (https://g-trap.000webhostapp.com/)• Constructed golden standard text mining repertoire on drug-drug interactions from pubmed articles.• Worked in collaboration with Dr. Mathew Palakal on sub-classifying cancers using Machine learning algorithms.• Analyzed huge RNA-seq datasets of pan-cancers to find significant genes among differentially expressed and methylated genes.• Network biology approach to investigate the effectiveness of Pooled CRISPR screening [CROP-Seq] methodology Show less

• Assisted senior/personnel in quality check of the pharmaceutical drugs. • Was a part of the sterilization team to ensure that the production equipment was safe and sterile.

• Worked with quality assurance team and chromatography lab and generated detailed reports on proteins. • Worked on spectrograph of proteins and created user defined views and reports from various database