Tom Tripodi Email & Phone Number

Marlboro Township, Nj, Us

Marlboro Township, Nj, Us

Us

• Compound Management and Drug Discovery Automation: Expertise in developing and seamlessly integrating a diverse array of instrument platforms for Compound Management and Drug Discovery Automation. • Automated qPCR Platform Development: Spearheaded the creation of an automated qPCR platform in collaboration with HighRes (HRB) Biosystems• Advanced Scheduling Program Proficiency: Highly skilled in crafting intricate scheduling programs using Cellario, Overlord2, and V-Works.• Assay Plate Creation Expert: Labcyte Echo Expert• Assay Development: Experienced in the strategic development of assays, contributing to enhanced screening processes. • Collaborative Drug Discovery: Effective development, oversight and execution of small molecule primary and confirmation screens, fostering collaboration with therapeutic teams to advance new drug target discovery.• Automation and Instrument Expertise: Extensive experience in Compound Management and Drug Discovery Automation and instrument integration, including HighRes Biosolutions, Beckman, Labcyte, Brooks, Azenta, Thermo, PerkinElmer, Agilent, Molecular Devices, EDC, and more. Proficient in programming with Cellario, Overlord2, and V-works scheduling software. • Custom Compound Management and Assay Plate Creation System: Led the development of a customized system integrating the Brooks / Azenta Universal Compound Store with downstream Acoustic and Assay Plate Creation technologies.• Design and Specification: Skilled in designing, specifying, and conducting acceptance testing for automated platforms. • Project Management and Leadership: Highly effective in project management and team leadership roles, ensuring the successful execution of complex initiatives.• Innovative Screening Paradigms: Enabled novel compound screening approaches by harnessing acoustic sample transfer technologies.• Global Compound Management Leadership: Acted as the site lead for a global compound management operation.

Us

Program robotic platforms and conduct primary small molecule screens for new drug targets in collaboration with therapeutic teams throughout PTC Therapeutics Inc.

Us

Kenilworth, New Jersey, Us

Assay development and High Throughput ScreeningCo-authored paper titled: "Screening for small molecule inhibitors of insulin-like growth factor receptor (IGF-1R) kinase: comparison of homogeneous time-resolved fluorescence and 33P-ATP plate assay formats"Wang Y, Malkowski M, Hailey J, Turek-Etienne T, Tripodi T, Pachter JA.J Exp Ther Oncol. 2004 Jul;4(2):111-9.

- Completed PCR project aimed to optimize and validate techniques and results in accordance with FDA and GMP guidelines - Extracted B19 and Parvovirus DNA from human blood plasma - Analyzed/diagnosed extractions through PCR amplification followed by PAGE and metaphor agarose detection- Prepared kinase PCR B19 primers using 32P -ATP- Detected viral B19 PCR product by radiography of the kinase primers through liquid hybridization - Analyzed and reported all data to FDA

Developed a process for nucleic acid molecular probe assembly using DNA hybridization- Evaluated the quality of single stranded DNA through native and denaturing gel electrophoresis- Performed Ultra-violet cross-linking and purification techniques via ultracentrifugation- Analyzed the final product through radioactive oligo ligation, and measured the outcome through native sucrose density gradients

Ms, Biochemistry

Bs, In Biology, Minor In Chemistry