Toño Estrada Email and Phone Number

Process/Development/R&D/Manufacture Chemist in R&D and cGMP setting in multi-step small and large scale synthesis. 6 years in CDMO/CRO and 10 years plus in Organic Synthesis. Independent and group collaboration synthesis, scale-up techniques (>1 Kg) and analytical methods at CRO/CDMO. Managing all aspect of project, cradle to grave including disposal with special needs. Synthesis involvements across multi-functional department development of API, known and unknown impurities markers, building blocks, amidites, dyes, linkers, thio, NHS-Esters and various others. Broad experience characterizing/use of analytical tools for small molecules with intent to transfer, scale-up including IPC development, final characterization and instrument maintenance (HPLC, NMR, KF, M.P, etc.)Proven leadership developing stable crystal form/conformation suitable for scale-up (>1 Kg) in API, penultimates, amidites synthesis and technology/technique transfer including instrumentation selection with less than 3% variance to Manufacturing group for continuous production. Team player mentoring junior chemist in arts of process chemistry, efficient instrumentation usage and synthesis techniques while adhering to safe scalable synthesis and waste management including lowering PMI. Experience developing, characterizing and writing new methods, SOP, Batch reports for safer manufacturing process and updating instrumentation in a CRO/CDMO environment including schedule III compound in cGMP setting.