Giel Hendriks Email & Phone Number

Leiden, ZH, NL

Oegstgeest, NL

Oegstgeest, NL

Toxys, a spin-out company from the Leiden University Medical Center, provides next-generation genotoxicity testing services to rapidly identify potential carcinogenic properties of novel compounds during the early phases of product and drug development. Every novel chemical compound that is developed by pharmaceutical, chemical, cosmetics or food companies.

Leiden, Zuid-Holland, NL

By combining whole genome transcription profiling, advanced genome editing tool and extensive stem cell expertise, we have developed various in vitro reporter systems that allow studying the mode of action of genotoxic chemicals. These reporter assays are used to provide a better understanding of how cells are responding to the induction of DNA damage.A.

Leiden, Zuid-Holland, NL

Our DNA is continuously exposed to factors that can damage the DNA. DNA damage can lead to the induction of mutations and subsequently to various genetic diseases including cancer. At the department of Toxicogenetics we are studying the cellular mechanisms involved in these DNA damage-induced mutations and the role of the different DNA repair systems that.

Title thesis: Synthesys and sorting of the Aquaporin-2 water channel.The Aquaporin-2 water channel plays an imporant role in resorption of water form the urine in the kidney. The research I performed during my PhD training was focussed on the cellular mechanisms that are involved in the biosynthesis and intracellular transport of the the water channels to.

Msc, Molecular Cell Biology

Education record