I am currently a postdoctoral researcher under supervision of Prof. Dario Alessi at the MRC Protein Phosphorylation and Ubiquitylation Unit, Dundee university and of Prof. Kei Sakamoto from Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen. I have been working on a main project to unravel novel phosphatases of AMPK. Additionally, I have been optimizing methods to selectively degrade phosphatases belong to PPM-type family based on PROTACs (proteolysis targeting chimera). This approach together with mass-spectrometry studies are used to identify potential novel substrates of these phosphatases. These works might be useful to developing improved treatments for Parkinson's disease and metabolic diseases such as type 2 diabetes. I obtained a PhD degree in Biochemistry and Biotechnology from Katholieke Universiteit (KU) Leuven, Belgium. In the lab of Prof. Patrick Van Dijck, I investigated the regulatory mechanism of trehalase enzyme in Arabidopsis thaliana, in order to engineer new transgenic plants with better drought stress tolerance.
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Postdoctoral ResearcherUniversity Of DundeeDundee, Gb
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Postdoctoral ResearcherUniversity Of Dundee Aug 2020 - PresentDundee, Scotland, United KingdomResponsibilities: - Plan, design, and conduct experiments involved in 3 projects: + Unravelling novel phosphatases of AMPK + Optimizing PROTACs to selectively degrade proteins + Using mass-spectrometry to identify novel substrates of PPM-type phosphatase family- Analyze data, prepare manuscripts/reportsProfessional skills:- SDS-PAGE, Western Blot, PCR- Crispr-Cas- Wide-genome screening- Protein expression (in prokaryotes as E. coli and eukaryotes such as yeast, mammalian cells), protein purification, protein-protein interaction (IP, Co-IP)- Phos-tag gels- Molecular cloning- Cell-based assays- DNA transfection (transient, stable)- Cell culture (HEK293, A549, HepG2, U2OS, MCF7)- Nucleic acid extraction
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Doctoral FellowKu Leuven Jun 2015 - Sep 2020Leuven, Flemish Region, BelgiumResponsibilities: - Plan, design, and conduct experiments involved in the projects: + investigating the regulatory mechanism of trehalase enzyme in Arabidopsis thaliana + engineering new transgenic plants with higher drought stress tolerance- Analyze data, prepare manuscripts/reports- Supervise bachelor/master thesis studentsProfessional skills:- SDS-PAGE, Western Blot, Northern Blot- PCR, RT-PCR, qPCR- Protein expression (in prokaryotes as E. coli and eukaryotes such as yeast, mammalian cells), protein purification, protein-protein interaction (IP, Co-IP)- Phos-tag gels- Molecular cloning- DNA transfection (transient, stable)- Nucleic acid extraction- Confocal microscopy- Generating transgenic plants -
LecturerCan Tho University Mar 2009 - May 2015Can Tho, VietnamResponsibility:- Teach Fundamental Biology (Theory and Practice), Biochemistry (Practice)- Research in essential oils- Supervise bachelor thesis students
Tran Phan Education Details
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Biotechnology
Frequently Asked Questions about Tran Phan
What company does Tran Phan work for?
Tran Phan works for University Of Dundee
What is Tran Phan's role at the current company?
Tran Phan's current role is Postdoctoral Researcher.
What schools did Tran Phan attend?
Tran Phan attended Ku Leuven, Chosun University.
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KhanhTran Phan
Operations Coordinator | Bachelor'S In International Business | Passionate About Logistics & Supply ChainHo Chi Minh City, Vietnam -
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