Responsible for coordinating and executing the automation strategy for laboratory sciences. Identify business opportunities in which laboratory automation will increase productivity of the project. Develop multiple complex liquid handling robotics systems that automate repetitive laboratory tasks where automation can drive quality, efficiency and/or throughput. Oversee and maintain project management and daily scheduling of automated instrumentation and 12 laboratory technicians in bioanalysis and biomarker fields within a production environment.Key Accomplishments:1. Led project to develop and validate fully automated bioanalysis ELISA for the detection of Generic Human Ig in both serum and plasma matrix using the Hamilton Microlab STARlet liquid handling workstation.2. Led project to develop and implement automated workflow for the creation of bioanalysis stock preparations to include all validation parameters (selectivity, dilution integrity, dilution linearity, precision and accuracy).

Oversaw technical and operational performance of the assigned laboratory science department (Automation department). Provided direct supervision and guidance in the day to day activities of 4 liquid handling robotics users. Developed and tracked technical and operational success through metrics and KPIs. Determined automation instrument capacity and developed scheduling which maximized automation production.Key Accomplishments:1. Implemented a 24/7 production team to include day, swing, and graveyard shift staffing which increased instrument utilization by 30% and reduced overtime.2. Managed all departmental T-Cell Dependent Antibody Response (TDAR) ELISA projects to include scoping work, scheduling in-lab execution, managing external resources such as QA audits, scientific review of data regressions, incorporating data QC teams and delivering final data report tables. Demonstrated a 12% decrease in assay failure rate.

Assisted department management with oversight and daily supervision and scheduling of 4 liquid handling robotics users, and automation production lines. Served as lead/primary technician and optimized complex automation solutions for automated liquid handling on specialized PK and TDAR KLH ELISA protocols. Provided leadership, technical guidance, and served as a mentor to less experienced staff.Key Accomplishments1. Led project to develop fully automated workflow for the generation of raw data paperwork, sample worklists, and data review sheets using Hamilton Venus programming to decrease project prep time from 16 hours to 1 hour.

Served as lead/primary technician for both basic and complex studies simultaneously. Functioned as a project scientist on specific projects as deemed appropriate by management. Responsible for developing and performing laboratory procedures. Developed new techniques, procedures, and scientific innovations that expand the capabilities of the department by implementing Hamilton Microlab STARlet liquid handling platforms. Provide leadership and technical guidance in the laboratory.Key Accomplishments:1. Validated the Hamilton Microlab STARlet liquid handling platform according to 21CFR part 11 compliance.2. Led project to design, develop, and validate fully automated TDAR and clinical bioanalysis TK/PK ELISA workflows on the Hamilton Micorlab STARlet liquid handling platform in which throughput increased 6x.3. Developed metrics for automated bioanalysis and TDAR projects to assist management in scoping work using the Hamilton platform.

SERVED AS LEAD/PRIMARY TECHNICIAN FOR BOTH BASIC AND MODERATELY COMPLEX STUDIES SIMULTANEOUSLY. MAINTAINED TIMELINES OF STUDIES AND NOTIFIED MANAGEMENT OF SCHEDULING NEEDS. RESPONSIBLE FOR DEVELOPING AND PERFORMING LABORATORY PROCEDURES. PROVIDE GUIDANCE AND MENTORSHIP TO LESS EXPERIENCED STAFF.Key Accomplishments:1. Led project to develop and implement bioanalysis sample dilutions on Eppendorf epMotion automated platform to increase throughput 3x over manual benchwork.2. Acted as lead analyst for multiple bioanalysis sample analysis studies, managing project timelines and scheduling needs, reagent inventory, and data regression.3. Acted as secondary analyst on method development and validation studies for TK/PK platforms.

Generated and recorded data with minimal supervision in the performance of studies according to GLP regulations. Responsible for handling and processing samples, and performing accurate data collection and reporting. Performed laboratory tasks by various basic methods, to include ELISA, DNA isolation, DNA quantitation, and QPCR.Key Accomplishments:1. Demonstrated proficiency in Molecular Biology DNA Isolation, quantitation, and QPCR.2. Gained solid understanding of GLP regulations and 21CFR part 11 compliance.3. Acted as main technician to perform bioanalysis benchwork for both clinical and preclinical TK/PK ELISA in support of sample analysis.

• Designed and constructed a genetically encoded cyclic adenosine monophosphate (cAMP) biosensor targeted to the nucleus of mammalian cells• Created an adenovirus that can be used to express the biosensor in cardiac myocytes• Demonstrated that the biosensor could respond to changes in cAMP activity produced by beta-adrenergic and/or prostaglandin receptor stimulation using FRET