Trevor Mcdaniel Email & Phone Number

Brentford, Middlesex, Gb

Senior Scientist for mass spectrometry and protein characterization in Collegeville, PA. Responsible for conducting mass spec-based experiments (e.g. LC-MS and LC-MS/MS) for the characterization of therapeutic proteins. Develop other analytical and/or biochemical methods to further understand the structure-function relationship of proteins, while supporting biopharmaceutical development from FTIH through commercial.

Newtown, Pa, Us

• Performed qualitative analysis for the following: oligonucleotides, small molecules, proteins, and peptides.• Managed 3 MS instruments daily for same day turnaround on hundreds of samples at exactitude.• Operated, calibrated, and maintained multiple Mass Spectrometry instruments for biomolecular analysis: Thermo LTQ-XL, Orbitrap Fusion Tribrid Mass Spectrometer, Thermo Orbitrap Vanquish and Discovery, Waters Xevo G2XS, & LC instruments and relevant software packages (e.g. Chromeleon, Chronos, Xcalibur, Masslynx) • Utilized Novatia’s ProMass software for data reporting and improved ProMass D3 Javascript code for data interpretation/reporting.• Manually adjusted LCMS methods and conditions to ensure quality analysis & accuracy.• Developed and tested liquid chromatography-mass spectrometry methods per customer project.• Communicated data and results to customers daily with extension of support for any questions or concerns.• Worked in an administrative capacity to optimize and streamline the sample submission process for our customers, as well as improve the overall efficiency of day-to-day operations.• Deployed and maintained a Dell PowerEdge ESXI Server to improve network infrastructure and security. • Upgraded Novatia’s infrastructure by employing up to date software for the following: robust FTP server, Veeam data and replication, optimization of VM resource allocation for data intensive programs (peptide mapping), and SNMP protocol.

Normal, Il, Us

Research in the Field of Analytical Chemistry (August 2019– July 2021)o Operated and maintained a prototype portable mass spectrometric (MS) instrumentation designed for on-site forensic investigation.o Fluent with multiple ionization techniques, including Electrospray Ionization (ESI), Liquid Chromatography Mass Spectrometry (LCMS), Paper Spray Ionization (PSI), Paper Cone Spray Ionization (PCSI), Filter Cone Spray Ionization (FCSI), and 3D-Printed Cone Spray Ionization (3D-PCSI).o Refined skills in data analysis (Microsoft Excel, Xcalibur and Griffin software), reporting and oral/written communication (Microsoft PowerPoint/Office).o Proficient in Chemical Instrument Maintenance for identifying, diagnosing, calibration, and resolving issues in following instrumentation and devices: High-Resolution Mass Spectrometer, Liquid Chromatography-Mass Spectrometer, High Performance Liquid Chromatography, 3D-Printers, and Oil Pumps.o Engineered 3D-printing methodologies to rapidly screen Chemical Warfare Agents samples.o Employed novel ambient ionization methods to analyze various complex pharmaceuticals.Relevant Skills and Instrument Types Utilizedo Volumetric solution preparation, method development, data analysis, data report, and presentation generation/delivery.o Experience with the following instrument types: LCQ-ion trap MS, Hybrid Quadrupole Orbitrap MS, Tandem MS, UV-Vis, HPLC, Raman, LC-MS, GC-MS.o Fluent with 3D printing software process and development for novel method development.o Assumed all roles and responsibilities of the Laboratory Manager in his absence.o Ability to convey technical information in a clear and concise manner to all employees at all levels of the organization.o Developed a LC-HRMS experiment and software method to analyze over 1500 drug samples efficiently.

Master'S Degree, Analytical Chemistry

Bachelor Of Science - Bs, Chemistry

Associate Of Science - As, Chemistry