Tyler Ash Email and Phone Number

Transactions include:BrickBio license/investmentExpedeon acquisition of immunology and proteomics businessApplied Stem Cell acquisition of CRISPR gene editing platformMarkerGene acquisition▪ Create financial models to determine valuations and support negotiations including DCFs, licensing models, and comparable companies analysis▪ Manage cross-functional team diligence between R&D, Finance, Legal, Logistics, Commercial, and HR▪ Prepare financial analysis for integration budgets and forecasts

▪ Review financial and scientific data, analyze assets, and engineer rNPV financial models. Lead due diligence and deliver impactful feedback. Generate non-confidential and confidential memorandums, DCFs, comparable companies and comparable transaction analyses.▪ Pioneer and execute business development efforts, successfully acquiring two clients to date.▪ Advised on 10 biotechnology client projects for sell-side product licensing and M&A to date. ▪ Possess FINRA Series 79 and 63 licenses.

▪ Review financial and scientific data, analyze assets, and engineer rNPV financial models. Lead due diligence and deliver impactful feedback. Generate non-confidential and confidential memorandums, DCFs, comparable companies and comparable transaction analyses.▪ Pioneer and execute business development efforts, successfully acquiring two clients to date.▪ Advised on four biotechnology client projects for sell-side product licensing and M&A to date. ▪ Directed a hiring process and trained a new investment banking analyst.▪ Possess FINRA Series 79 and 63 licenses.

▪ Assessed clinical trial protocols and developed internal budgets used to negotiate with pharmaceutical sponsors and contract research organizations. • Reviewed clinical trial contracts for routine changes and compliance to negotiated budgets.▪ Managed collaborations with the research administration post-award office and hospital billing departments to ensure accurate and efficient budget and contract systems.

▪ Generated novel molecular tools to study GCC2 protein in neurodevelopment.▪ Coordinated research, and collected and analyzed data sets to test hypotheses. ▪ Managed and trained five laboratory members in scientific reasoning and experimental techniques.▪ Mastered various molecular and cellular biology techniques including cloning, infection and transfection of cell cultures, Western Blot, immunohistochemistry, immunocytochemistry, co-immunoprecipitation, confocal microscopy, and aseptic subculturing techniques. ▪ Worked with mice as models for development and presented research data as well as journal papers in lab meetings and journal club.Lab Rotations:• Host-microbe interactions in Drosophila stem cell niche lab • Medicinal chemistry lab• Laboratory of neural development and intellectual disorders

• Wrote portions of federal grant proposals and reports, public policy papers, articles for newsletters, and created posters to be presented at conferences• Scheduled conference between multiple PIs, created the agenda, and participated in the conference• Assisted in management of grant budget• Designed multiple experiments, and collected and analyzed data• Dissected arthropods, managed databases, executed in vitro bio-assays, and performed field work

• Research funded for $1,000 by National Science Foundation• Conducted gene transformations from E. coli to N. gonorrheae for antibiotic resistance• Extracted DNA and sequenced to confirm the species of a probioitic, Lactobacillus• Executed general lab duties such as autoclaving, plate pouring, general lab safety and cleaning

• Pursued, presented, and defended results on a research project aimed at developing a PCR-based diagnostic assay for the mutation E6V known to cause sickle cell anemia.• GPerformed PCR, DNA sequence analysis, primer design, agarose gel electrophoresis with both TBE and rapid Lithium Borate.• Initiated a secondary aspect to the research project by applying intentional mismatches in oligonucleotide primer sequence as proposed by Yaku et al [Electrophoresis, 2008], resulting in a wider annealing temperature range in PCR for hard to detect single nucleotide polymorphisms (SNPs).