Tyrone D. Email & Phone Number

Bethesda, Maryland, United States

LC-MS metabolomic, lipidomic, quantitative, and pharmacokinetic (PK) analysis for Oncological, Immunological, Neurodegenerative, Pathogenic and Pharmaceutical studies. Apply data analytic and data interpretation techniques to identify biomarkers, determine pathways of drug action and resistance, and conduct drug discovery. Application development and bioanalytical assay validation. Drug candidate assessment using in vitro and in vivo models. Metabolite, lipid, RNA and protein extraction from clinical patient, xenograph mouse, and cell specimens. Maintain mammalian cell cultures. Present research at conferences and meetings. SOP preparation and training for staff/interns.

Washington, District Of Columbia, United States

LC and GC-MS metabolomic, lipidomic, and quantitative analysis using MS/MS, SRM, MRM and ion mobility for the Proteomics and Metabolomics Shared Resource for the Lombardi Comprehensive Cancer Center. Application development and optimization for clinical patient and pre-clinical mouse studies. Manage and conduct studies for internal and external contracts in Core facilities. Process human and mouse specimens. Perform R-based data analytics and data interpretation. Prepare and present comprehensive data reports. Provide instruction to doctoral candidate and undergraduate class on data analytic techniques.

Manassas, Virginia, United States

LC-MS/MS-based identification and quantification of small molecules for rational drug discovery. Design and conduct research to screen natural products for lead candidate research and development. Perform protein purification for crystallography and kinetic assays. Develop SOPs for QTOF LC-MS/MS operations, sample preparation, and experimental procedures. Mentor and train interns on research procedures.

Fairfax County, Virginia, United States

Prepared lectures, manage experiments, and review lab reports and notebooks to support mastery of organic, environmental, and commercial chemistry laboratory techniques and principles for undergraduate classes.